Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human P4HA1

Cat.No. : P4HA1-30543TH
Product Overview : Recombinant full length Human P4HA1 with a N terminal proprietary tag; Predicted MWt 84.81 kDa including the tag.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
Protein length : 534 amino acids
Molecular Weight : 84.810kDa inclusive of tags
Source : Wheat germ
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVT SLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGH PVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKS FLTAEDCFELGKVAYTEADYYHTELWMEQALRQLDEGEIS TIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAV DYLPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPK FILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL RRATISNPITGDLETVHYRISKSAWLSGYENPVVSRINMR IQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDA FKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKG TAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHER GQEFRRPCTLSELE
Sequence Similarities : Belongs to the P4HA family.Contains 1 Fe2OG dioxygenase domain.Contains 1 TPR repeat.
Gene Name : P4HA1 prolyl 4-hydroxylase, alpha polypeptide I [ Homo sapiens ]
Official Symbol : P4HA1
Synonyms : P4HA1; prolyl 4-hydroxylase, alpha polypeptide I; P4HA, procollagen proline, 2 oxoglutarate 4 dioxygenase (proline 4 hydroxylase), alpha polypeptide I; prolyl 4-hydroxylase subunit alpha-1; C P4Halpha(I); collagen prolyl 4 hydroxylase alpha(I);
Gene ID : 5033
mRNA Refseq : NM_000917
Protein Refseq : NP_000908
MIM : 176710
Uniprot ID : P13674
Chromosome Location : 10q21.3-q23.1
Pathway : Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem;
Function : L-ascorbic acid binding; binding; iron ion binding; metal ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into bo;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All P4HA1 Products

Required fields are marked with *

My Review for All P4HA1 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends