Recombinant Human Tumor Necrosis Factor Receptor Superfamily, Member 1A
Cat.No. : | TNFRSF1A-1577H |
Product Overview : | Recombinant Human TNF receptor (P55) extracellular domain is produced in genetically engineeredSpodoptera frugiperda insect cells (Sf9)infected with recombinant viruses, and purified by sequential chromatography. |
- Specification
- Gene Information
- Related Products
Cat. No. : | TNFRSF1A-1577H |
Description : | TNFR1 belongs to the TNFR superfamily of transmembrane proteins, and is expressed in most cell types. Binding of either TNF-alpha or TNF-beta to TNFR1 initiates a signal transduction pathway that results in the activation of the transduction factor NFkB, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells induce apoptosis. |
Source : | Sf9. |
Availability : | Check availability. |
Isotype : | N/A. |
Purity : | Over 80% pure. Three bands are observed by SDS gel electrophoresis, however, a single band is observed after glycosidase treatment, indicating heterogeneity in the sugar portion of this glycoprotein. |
Formulation : | 10 mM Hepes, pH 7.0. Concentration: 1.0 mg protein/ml. |
Biological Activity : | Binding of the ligand TNF was demonstrated by receptor binding competition of binding with radioactive TNF. |
Stability : | At least 2 months at -80°C. |
Storage : | Store at -80°C. |
Gene Name : | TNFRSF1A tumor necrosis factor receptor superfamily, member 1A [ Homo sapiens ] |
Synonyms : | TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A; FPF; p55; p60; TBP1; TNF-R; TNFAR; TNFR1; p55-R; CD120a; TNFR55; TNFR60; TNF-R-I; TNF-R55; MGC19588; tumor necrosis factor binding protein 1; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor type 1; tumor necrosis factor-alpha receptor |
Gene ID : | 7132 |
mRNA Refseq : | NM_001065 |
Protein Refseq : | NP_001056 |
MIM : | 191190 |
UniProt ID : | P19438 |
Chromosome Location : | 12p13.2 |
Pathway : | Adipocytokine signaling pathway; Alzheimer"s disease; Amyotrophic lateral sclerosis (ALS); Apoptosis; Cytokine-cytokine receptor interaction; MAPK signaling pathway; MAPK signaling pathway; Apoptosis |
Function : | protein complex binding; receptor activity; tumor necrosis factor receptor activity |
Products Types
◆ Recombinant Protein | ||
Tnfrsf1a-314M | Recombinant Mouse TNFRSF1A Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
Tnfrsf1a-10624M | Recombinant Mouse Tnfrsf1a Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFRSF1A-444H | Recombinant Human TNFRSF1A Protein, His-tagged | +Inquiry |
TNFRSF1A-149H | Recombinant Human TNFRSF1A Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFRSF1A-203T | Active Recombinant Human TNFRSF1A Protein | +Inquiry |
◆ Lysates | ||
TNFRSF1A-1084RCL | Recombinant Rat TNFRSF1A cell lysate | +Inquiry |
TNFRSF1A-1693MCL | Recombinant Mouse TNFRSF1A cell lysate | +Inquiry |
TNFRSF1A-2390HCL | Recombinant Human TNFRSF1A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket