Recombinant Human Human PIK3CG, His-tagged
Cat.No. : | PIK3R5-31760TH |
Product Overview : | Human recombinant Full Length proteins: PI 3 Kinase catalytic subunit gamma and PIK3R5.The PI 3 Kinase catalytic subunit gamma carries a N-terminal X6His Tag, whereas the PIK3R5 adaptor subunit carries a N-terminal enzyme tag.The molecular weight for PI 3 |
- Specification
- Gene Information
- Related Products
Description : | Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. |
Conjugation : | HIS |
Biological activity : | Activity: ~ 3 nmol/mg/min using phosphatidylinositol as the substrate. |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 50% Glycerol, 25mM Sodium chloride, 25mM HEPES, 2.5mM Magnesium chloride, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Gene Name : | PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 [ Homo sapiens ] |
Official Symbol : | PIK3R5 |
Synonyms : | PIK3R5; phosphoinositide-3-kinase, regulatory subunit 5; phosphoinositide 3-kinase regulatory subunit 5; p101; P101 PI3K; |
Gene ID : | 23533 |
mRNA Refseq : | NM_001251852 |
Protein Refseq : | NP_001238781 |
MIM : | 611317 |
Uniprot ID : | Q8WYR1 |
Chromosome Location : | 17p13.1 |
Pathway : | 3-phosphoinositide biosynthesis, conserved biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; |
Function : | 1-phosphatidylinositol-3-kinase regulator activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; |
Products Types
◆ Recombinant Protein | ||
PIK3R5-1084H | Recombinant Human PIK3R5 Protein (1-494 aa), His-SUMO-tagged | +Inquiry |
PIK3R5-2400C | Recombinant Chicken PIK3R5 | +Inquiry |
◆ Lysates | ||
PIK3R5-3182HCL | Recombinant Human PIK3R5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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