Recombinant Human PRDX2, His-tagged
Cat.No. : | PRDX2-29680TH |
Product Overview : | Recombinant full length Human Peroxiredoxin 2 with N-terminal His tag expressed in a Baculovirus infected Sf9 cell expression system, 22.7 kDa. |
- Specification
- Gene Information
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Description : | This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms. Transcript variants encoding distinct isoforms have been identified for this gene. |
Conjugation : | HIS |
Biological activity : | Specific Activity: 149 pmol/min/μg.3.45 μg of Peroxiredoxin 2 was incubated in 50 mM Hepes (pH 7.0) containing 200 μM NADPH, 3 μM thioredoxin, and 1.5 μM thioredoxin reductase. The reaction mixture was incubated at 30C for 5 min, followed by the addition |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8 |
Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the ahpC/TSA family.Contains 1 thioredoxin domain. |
Gene Name : | PRDX2 peroxiredoxin 2 [ Homo sapiens ] |
Official Symbol : | PRDX2 |
Synonyms : | PRDX2; peroxiredoxin 2; TDPX1; peroxiredoxin-2; MGC4104; natural killer enhancing factor B; NKEFB; PRP; PRX2; PRXII; thiol specific antioxidant 1; thioredoxin peroxidase 1; thioredoxin dependent peroxide reductase 1; torin; TSA; |
Gene ID : | 7001 |
mRNA Refseq : | NM_005809 |
Protein Refseq : | NP_005800 |
MIM : | 600538 |
Uniprot ID : | P32119 |
Chromosome Location : | 19p13.2 |
Pathway : | Selenium Pathway, organism-specific biosystem; |
Function : | antioxidant activity; antioxidant activity; oxidoreductase activity; thioredoxin peroxidase activity; thioredoxin peroxidase activity; |
Products Types
◆ Recombinant Protein | ||
PRDX2-333H | Recombinant Human PRDX2 Protein, His/GST-tagged | +Inquiry |
PRDX2-2910H | Recombinant Human PRDX2 Protein, MYC/DDK-tagged | +Inquiry |
PRDX2-2247H | Recombinant Human PRDX2 Protein (2-198 aa), His-tagged | +Inquiry |
Prdx2-5102M | Recombinant Mouse Prdx2 Protein, Myc/DDK-tagged | +Inquiry |
PRDX2-332H | Recombinant Human PRDX2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PRDX2-564HCL | Recombinant Human PRDX2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionPRDX2's role in maintaining cellular redox balance implicates it in cancer progression. Modulating PRDX2 levels may offer avenues for developing novel cancer therapies.
As with any targeted therapy, potential side effects need thorough investigation. Modulating PRDX2 levels could impact normal cellular functions, and careful assessment is required.
Some studies suggest that PRDX2 levels may have prognostic value in diseases associated with oxidative stress, providing insights into disease progression.
Yes, PRDX2 is a potential drug target, but challenges include developing specific modulators and understanding the protein's complex regulatory mechanisms.
Research suggests that altered levels of PRDX2 could serve as a biomarker in diseases associated with oxidative stress, offering potential diagnostic applications.
Customer Reviews (3)
Write a reviewI am eager to embark on this scientific journey, empowered by the high-quality PRDX2 protein and the manufacturer's unparalleled assistance.
The manufacturer's prompt and reliable technical support serves as an invaluable resource, reinforcing my confidence in the PRDX2 protein's effectiveness and enabling smooth progress in my experiments.
Its remarkable purity and functional attributes make it an optimal choice for my research, ensuring accurate and reliable outcomes.
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