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Recombinant Mouse Frizzled Homolog 4 (Drosophila)

Cat.No. : Fzd4-1740M
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  • Gene Information
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Cat. No. : Fzd4-1740M
Description : Frizzled-4 (FZD4) is a Frizzled Receptor involved in mediating Wnt signaling that is widely expressed, particularly in heart, skeletal muscle, ovary, and fetal kidney. FZD4 functions as a ligand-receptor pair to control vascular development in the retina and inner ear. Fz4 expression may play a critical role in responses to Wnt signaling in the tumor microenvironment.
Molecular Weight : The predicted molecular weight of Recombinant Mouse Frizzled-4 is Mr 43 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 55-50 kDa.
Source : Mammalian cells
State Of Matter : Lyophilized.
Purity : >95% by SDS Page and analyzed by silver stain.
Formulation : This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : Fzd4 frizzled homolog 4 (Drosophila) [ Mus musculus ]
Synonyms : Fzd4; frizzled homolog 4 (Drosophila);Fz4; frizzled 4
Gene ID : 14366
mRNA Refseq : NM_008055
Protein Refseq : NP_032081
UniProt ID : Q61088
Chromosome Location : 7 E1; 7 44.5 cM
Pathway : Basal cell carcinoma; Colorectal cancer; Melanogenesis; Pathways in cancer; Wnt signaling pathway
Function : G-protein coupled receptor activity; non-G-protein coupled 7TM receptor activity; protein binding; receptor activity; signal transducer activity; transmembrane receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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