Recombinant Rat Growth Hormone Receptor
Cat.No. : | Ghr-1792R |
- Specification
- Gene Information
- Related Products
Cat. No. : | Ghr-1792R |
Description : | Growth hormone receptor, also known as GHR is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature (proportional dwarfism). |
Molecular Weight : | The predicted molecular weight of Recombinant Rat GHR is Mr 55.1 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 65-80 kDa. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >90% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | Ghr growth hormone receptor [ Rattus norvegicus ] |
Synonyms : | Ghr; growth hormone receptor; GHR/BP; MGC124963; MGC156665; growth hormone receptor/binding protein |
Gene ID : | 25235 |
mRNA Refseq : | NM_017094 |
Protein Refseq : | NP_058790 |
UniProt ID : | P16310 |
Chromosome Location : | 2q16 |
Pathway : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Neuroactive ligand-receptor interaction |
Function : | SH2 domain binding; growth hormone receptor activity; peptide hormone binding; phosphate binding; protein binding; protein homodimerization activity; protein kinase binding; protein phosphatase binding; receptor activity |
Products Types
◆ Recombinant Protein | ||
GHR-1279R | Acitve Recombinant Rat GHR protein(Met1-Arg265), hFc-tagged | +Inquiry |
Ghr-3269M | Active Recombinant Mouse Ghr protein(Met1-Gln273), His-tagged | +Inquiry |
GHR-280H | Recombinant Human GHR Protein, Fc-tagged | +Inquiry |
Ghr-56M | Recombinant Mouse Ghr Protein, His (Fc)-Avi-tagged | +Inquiry |
Ghr-6382R | Recombinant Rat Ghr Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
GHR-2401MCL | Recombinant Mouse GHR cell lysate | +Inquiry |
GHR-1140RCL | Recombinant Rat GHR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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