Recombinant Human RBP4, FLAG-tagged

• Cat.No.: RBP4-30009TH
• Product Overview: Recombinant full length Human RBP4 fused at the N terminus to a DDDDK tag; mwt: 23 kDa.

Specification

• Description: This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.
• Protein length: 183 amino acids
• Conjugation: FLAG
• Molecular Weight: 23.000kDa
• Source: HEK 293 cells
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: PBS, pH 7.2
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the calycin superfamily. Lipocalin family.

Gene Information

• Gene Name: RBP4 retinol binding protein 4, plasma [ Homo sapiens ]
• Official Symbol: RBP4
• Synonyms: RBP4; retinol binding protein 4, plasma; retinol-binding protein 4
• Gene ID: 5950
• mRNA Refseq: NM_006744
• Protein Refseq: NP_006735
• Uniprot ID: P02753
• Chromosome Location: 10q23-q24
• Pathway: Vitamin A and carotenoid metabolism, organism-specific biosystem
• Function: protein binding; retinal binding; retinol binding; retinol transporter activity; transporter activity