Recombinant Human ROCK2
Cat.No. : | ROCK2-30955TH |
Product Overview : | Recombinant fusion protein, corresponding to amino acids 5-554 of Human ROCK2 with an N-terminal tag, expressed by baculovirus in Sf9 insect cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. |
Biological activity : | Specific activity 350 nmol/min/mg. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.Contains 1 AGC-kinase C-terminal domain.Contains 1 PH domain.Contains 1 phorbol-ester/DAG-type zinc finger.Contains 1 protein kinase domain.Contains 1 REM (Hr1) repeat. |
Gene Name : | ROCK2 Rho-associated, coiled-coil containing protein kinase 2 [ Homo sapiens ] |
Official Symbol : | ROCK2 |
Synonyms : | ROCK2; Rho-associated, coiled-coil containing protein kinase 2; rho-associated protein kinase 2; |
Gene ID : | 9475 |
mRNA Refseq : | NM_004850 |
Protein Refseq : | NP_004841 |
MIM : | 604002 |
Uniprot ID : | O75116 |
Chromosome Location : | 2p24 |
Pathway : | Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; |
Function : | ATP binding; metal ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; |
Products Types
◆ Recombinant Protein | ||
ROCK2-1879H | Active Recombinant Human ROCK2 Protein, His-tagged | +Inquiry |
Rock2-2026R | Recombinant Rat Rock2 Protein, His-tagged | +Inquiry |
ROCK2-37M | Recombinant Active Mouse ROCK2 Protein (5-554), N-His-tagged | +Inquiry |
Rock2-5568M | Recombinant Mouse Rock2 Protein, Myc/DDK-tagged | +Inquiry |
ROCK2-3769R | Recombinant Rhesus Macaque ROCK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ROCK2-2255HCL | Recombinant Human ROCK2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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