Native Human SERPINA7

• Cat.No.: SERPINA7-30623TH
• Product Overview: Full length native Human Thyroxine Binding Globulin amino acids 21-415, purified from Human plasma. Predicted MWt 44kDa,

Specification

• Description: There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3 -triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
• Protein length: 395 amino acids
• Molecular Weight: 44.000kDa
• Form: Lyophilised:Use of phosphate buffer, pH >7.0 containing 0.15M NaCl is recommended.
• Purity: by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 0.02M Ammonium bicarbonate. May contain traces of buffer salts.
• Storage: Store at +4°C.

Gene Information

• Gene Name: SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 [ Homo sapiens ]
• Official Symbol: SERPINA7
• Synonyms: SERPINA7; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; serine (or cysteine) proteinase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 7 , TBG; thyroxine-binding globulin; alpha 1 antiproteinase; an
• Gene ID: 6906
• mRNA Refseq: NM_000354
• Protein Refseq: NP_000345
• Uniprot ID: P05543
• Chromosome Location: Xq21-q22
• Function: binding; hormone binding; serine-type endopeptidase inhibitor activity