Native Human SERPINF2

• Cat.No.: SERPINF2-27292TH
• Product Overview: Full length native Alpha 2 Antiplasmin purified from human plasma, 70kDa.

Specification

• Description: This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
• Biological activity: Specific activity:13.05 IU/mgSERPINF2-27292TH efficiently inhibits the plasminogen-activator-induced lysis of fibrin clots.
• Form: Lyophilised:Reconstitution is batch dependent. We deliver 100ug lyophilised product. Please add the correct volume of distilled water to achieve the lot specific concentration indicated on the vial.
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 200mM Sodium chloride, 20mM Bis-Tris, pH 6.4
• Storage: Store at -20°C. Stable for 12 months at -20°C

Gene Information

• Gene Name: SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 [ Homo sapiens ]
• Official Symbol: SERPINF2
• Synonyms: SERPINF2; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2; PLI, serine (or cysteine) proteinase inhibitor, clade F (alpha 2 antiplasmin, pigment epithelium derived factor), member 2; alpha-2-antiplas
• Gene ID: 5345
• mRNA Refseq: NM_000934
• Protein Refseq: NP_000925
• MIM: 613168
• Uniprot ID: P08697
• Chromosome Location: 17pter-p12
• Pathway: Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Dissolution of Fibrin Clot, organism-specific biosystem
• Function: endopeptidase inhibitor activity; protease binding; protein binding; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity