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Recombinant Human SMARCC2

Cat.No. : SMARCC2-31424TH
Product Overview : Recombinant full length Human SMRC2 isoform 2 with a N terminal proprietary tag; Predicted MWt 150.30 kDa.
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  • Gene Information
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Description : The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein length : 1130 amino acids
Molecular Weight : 150.300kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Ubiquitously expressed.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQ AEPPTNKSLSSLVVQLLQFQEEVFGKHVSNAPLTKLPIKC FLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDII KRHQGTVTEDKNNASHVVYPVPGNLEEEEWVRPVMKRDKQ VLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDE VNSPDSDRRDKKGGNYKKRKRSPSPSPTPEAKKKNAKKGP STPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENST GNKGEQTKNPDLHEDNVTEQTHHIIIPSYAAWFDYNSVHA IERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRP TPMGPPPTSHFHVLADTPSGLVPLQPKTPQGRQVDADTKA GRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLL LEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYL EDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKA DPAFGLESSGIAGTTSDEPERIEESGNDEARVEGQATDEK KEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKV ERDIGEGNLSTAAAAALAAAAVKAKHFAAVEERKIKSLVA LLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGS QPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS PFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSP GTVTPVPPPQ
Sequence Similarities : Belongs to the SMARCC family.Contains 1 SANT domain.Contains 1 SWIRM domain.
Gene Name : SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 [ Homo sapiens ]
Official Symbol : SMARCC2
Synonyms : SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2; SWI/SNF complex subunit SMARCC2; BAF170; CRACC2; Rsc8;
Gene ID : 6601
mRNA Refseq : NM_139067
Protein Refseq : NP_620706
MIM : 601734
Uniprot ID : Q8TAQ2
Chromosome Location : 12q13.2
Pathway : Glucocorticoid receptor regulatory network, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem;
Function : DNA binding; protein binding; transcription coactivator activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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