Recombinant Human Poly (ADP-ribose) Polymerase 2, GST-tagged

• Cat.No.: PARP2-433H
• Product Overview: Recombinant Human PARP2, amino-acids 2-583 with N-terminal GST tag expressed in aBaculovirusinfected Sf9 cell expression system. MW = 92kDa.

Specification

• Cat. No.: PARP2-433H
• Description: Poly (ADP-ribose) polymerase (PARP) is a protein involved in a number of cellular processes involving mainly DNA repair and programmed cell death.
• Source: Sf9 cell.
• Purity: >80%.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
• Stability: >6 months at –80°C.

Gene Information

• Gene Name: PARP2 poly (ADP-ribose) polymerase 2 [ Homo sapiens ]
• Synonyms: PARP2; poly (ADP-ribose) polymerase 2; ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2; poly (ADP-ribose) polymerase family, member 2; poly (ADP-ribosyl) transferase-like 2; poly(ADP-ribose) synthetase; EC 2.4.2.30; ADPRT2; PARP-2; ADPRTL2; ADPRTL3; pADPRT-2
• Gene ID: 10038
• mRNA Refseq: NM_001042618
• Protein Refseq: NP_001036083
• MIM: 607725
• UniProt ID: Q9UGN5
• Chromosome Location: 14q11.2-q12
• Pathway: Base excision repair
• Function: DNA binding; NAD or NADH binding; NAD+ ADP-ribosyltransferase activity; identical protein binding; protein N-terminus binding; transcription factor binding; transferase activity, transferring glycosyl groups; zinc ion binding