Recombinant Human SRPR, His-tagged

• Cat.No.: SRPR-29990TH
• Product Overview: Recombinant fragment, corresponding to amino acids 194-638 of Human SRPR alpha with N terminal His tag; 445 amino acids, 56kDa.

Specification

• Description: The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple transcript variants.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 86 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium hydrogen phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: LPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTK SDAPKEKGKKAPRVWELGGCANKEVLDYSTPTTNGTPE AALSEDINLIRGTGSGGQLQDLDCSSSDDEGAAQNSTK PSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRD HLIAKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQ ALQESLVQILQPQRRVDMLRDIMDAQRRQRPYVVTFCG VNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVE QLRTHTRRLSALHPPEKHGGRTMVQLFEKGYGKDAAGI AMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLITV NTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTP RLIDGIVLTKFDTIDDKVGAAISMTYITSKPIVFVGTG QTYCDLRSLNAKAVVAALMKA

Gene Information

• Gene Name: SRPR signal recognition particle receptor (docking protein) [ Homo sapiens ]
• Official Symbol: SRPR
• Synonyms: SRPR; signal recognition particle receptor (docking protein); signal recognition particle receptor subunit alpha; Sralpha; SRP alpha
• Gene ID: 6734
• mRNA Refseq: NM_003139
• Protein Refseq: NP_003130
• MIM: 182180
• Uniprot ID: P08240
• Chromosome Location: 11q24-q25
• Pathway: Activation of Chaperones by IRE1alpha, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Insulin Synthesis and Processing, organism-specific biosystem; Protein export, organism-specific biosystem; Protein export, conserved biosystem
• Function: GTP binding; GTPase activity; nucleotide binding; receptor activity; signal recognition particle binding