Recombinant Human SSR1

• Cat.No.: SSR1-31606TH
• Product Overview: Recombinant fragment of Human TRAP alpha with N-terminal proprietary tag, 54.05 kDa.

Specification

• Description: The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical.
• Protein length: 254 amino acids
• Molecular Weight: 54.050kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: QDLTEDEETVEDSIIEDEDDEAEVEEDEPTDLVEDKEEED VSGEPEASPSADTTILFVKGEDFPANNIVKFLVGFTNKGT EDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQA TFEYSFIPAEPMGGRPFGLVINLNYKDLNGNVFQDAVFNQ TVTVIEREDGLDGETIFMYMFLAGLGLLVIVGLHQLLESR KRKRPIQKVEMGTSSQNDVDMSWIPQETLNQINKASPRRL PRKRAQKRSVGSDE
• Sequence Similarities: Belongs to the TRAP-alpha family.

Gene Information

• Gene Name: SSR1 signal sequence receptor, alpha [ Homo sapiens ]
• Official Symbol: SSR1
• Synonyms: SSR1; signal sequence receptor, alpha; translocon-associated protein subunit alpha; translocon associated protein alpha; TRAPA
• Gene ID: 6745
• mRNA Refseq: NM_003144
• Protein Refseq: NP_003135
• MIM: 600868
• Uniprot ID: P43307
• Chromosome Location: 6p24.3
• Pathway: Activation of Chaperones by IRE1alpha, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Insulin Synthesis and Processing, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem
• Function: signal sequence binding