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Native Human TF

Cat.No. : TF-31156TH
Product Overview : Full length native Human Transferrin purified from human plasma.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum.
Tissue specificity : Expressed by the liver and secreted in plasma.
Biological activity : TF-31156TH has an iron binding capacity of 1.2 to 1.6ug/mg.
Form : Lyophilised:Reconstitute with 5.62ml distilled water.
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10mM PBS, pH 7.4
Storage : Store at -20°C. Stable for 12 months at -20°C
Sequence Similarities : Belongs to the transferrin family.Contains 2 transferrin-like domains.
Gene Name : TF transferrin [ Homo sapiens ]
Official Symbol : TF
Synonyms : TF; transferrin; serotransferrin; PRO1557; PRO2086;
Gene ID : 7018
mRNA Refseq : NM_001063
Protein Refseq : NP_001054
MIM : 190000
Uniprot ID : P02787
Chromosome Location : 3q21
Pathway : EPHB forward signaling, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; Hemostasis, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Mineral absorption, organism-specific biosystem;
Function : ferric iron binding; metal ion binding; protein binding; ubiquitin protein ligase binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can TF proteins be used for diagnosing diseases? 03/19/2021

Yes, abnormalities in TF proteins can serve as diagnostic markers for certain diseases.

Are there any approved drugs that target TF proteins? 11/27/2020

Yes, some drugs target TF proteins, especially in the treatment of cancer.

How do TF proteins contribute to autoimmune diseases? 08/25/2020

TF proteins can trigger or suppress immune responses, making them relevant in understanding autoimmune diseases.

How do TF proteins play a crucial role in clinical applications? 03/16/2016

TF proteins are vital for understanding disease mechanisms and can be targeted for therapeutic purposes.

Are there any clinical tests or assays that measure TF protein levels? 03/05/2016

Yes, various assays, like ELISA and Western blot, can be used to quantify TF protein levels.

Customer Reviews (3)

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Reviews
08/01/2020

    Their team of experts is not only knowledgeable about the TF protein but is also dedicated to assisting researchers like myself in overcoming any challenges that may arise.

    01/22/2018

      This high-quality protein is crucial for the success of my experiments, ensuring that I obtain reliable and meaningful scientific findings.

      04/11/2016

        The TF protein is of exceptional quality, making it a perfect fit for my experimental needs.

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