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Recombinant Human PTPN14, GST-tagged

Cat.No. : PTPN14-454H
Product Overview : Recombinant Human Catalytic domain, (a.a. 817-1188), with N-terminal GST tag expressed in anE.coliexpression system. MW= 61 kDa.
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  • Gene Information
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Cat. No. : PTPN14-454H
Description : Tyrosine-protein phosphatase non-receptor type 14 is an enzyme that in humans is encoded by the PTPN14 gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. The specific function of this PTP has not yet been determined.
Source : E.Coli.
Purity : >90% by SDS-PAGE.
Application : Useful for the study of enzyme kinetics, regulation, to dephosphorylate target substrates and for screening inhibitors.
Formulated In : 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol, 2 mM EDTA, 1 mM DTT, 10 mM glutathione.
Stability : >12 months at –80°C.
Gene Name : PTPN14 protein tyrosine phosphatase, non-receptor type 14 [ Homo sapiens ]
Synonyms : PTPN14; protein tyrosine phosphatase, non-receptor type 14; PEZ; PTP36; MGC126803; cytoskeletal-associated protein tyrosine phosphatase; EC 3.1.3.48; Tyrosine-protein phosphatase non-receptor type 14; Protein-tyrosine phosphatase pez
Gene ID : 5784
mRNA Refseq : NM_005401
Protein Refseq : NP_005392
MIM : 603155
UniProt ID : Q15678
Chromosome Location : 1q32.2
Function : binding; hydrolase activity; protein tyrosine phosphatase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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