Recombinant Human TIMP4

• Cat.No.: TIMP4-31152TH
• Product Overview: Recombinant full length Human TIMP4 protein purified from transfected human kidney cells.

Specification

• Description: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.
• Tissue specificity: Abundant in heart and present at low levels in many other tissues.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: 0.01% Sodium AzideConstituents: 10mM MES, 50% Glycerol, 0.02% Brij 35, 300mM Sodium chloride, pH 5.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protease inhibitor I35 (TIMP) family.Contains 1 NTR domain.

Gene Information

• Gene Name: TIMP4 TIMP metallopeptidase inhibitor 4 [ Homo sapiens ]
• Official Symbol: TIMP4
• Synonyms: TIMP4; TIMP metallopeptidase inhibitor 4; tissue inhibitor of metalloproteinase 4; metalloproteinase inhibitor 4
• Gene ID: 7079
• mRNA Refseq: NM_003256
• Protein Refseq: NP_003247
• MIM: 601915
• Uniprot ID: Q99727
• Chromosome Location: 3p25
• Pathway: Matrix Metalloproteinases, organism-specific biosystem
• Function: enzyme inhibitor activity; metal ion binding; metalloendopeptidase inhibitor activity