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Recombinant Human SET Domain Containing 2, GST-tagged

Cat.No. : SETD2-460H
Product Overview : Recombinant Human SETD2 (amino acids 915-1211) was expressed in anE.coliexpression system with N-terminal GST tag. MW=59.7 kDa.
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  • Gene Information
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Cat. No. : SETD2-460H
Description : Histone-lysine N-methyltransferase SETD2 is an enzyme that in humans is encoded by the SETD2 gene. Huntington"s disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs.
Source : E.Coli.
Formulated In : 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
Application : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Purity : > 75%.
Stability : >6 months at –80°C.
Gene Name : SETD2 SET domain containing 2 [ Homo sapiens ]
Synonyms : SET domain containing 2; HYPB; SET2; HIF-1; KMT3A; HBP231; HSPC069; p231HBP; FLJ16420; FLJ22472; FLJ23184; FLJ45883; FLJ46217; KIAA1732; SETD2; huntingtin yeast partner B; lysine N-methyltransferase 3A; SET domain-containing protein 2; huntingtin interacting protein 1; huntingtin-interacting protein B; histone-lysine N-methyltransferase SETD2; EC 2.1.1.43; HIF1; hSET2; Huntingtin yeast partner B; Huntingtin-interacting protein 1; Huntingtin-interacting protein B; Lysine N-methyltransferase 3A
Gene ID : 29072
mRNA Refseq : NM_014159
Protein Refseq : NP_054878
MIM : 612778
UniProt ID : Q9BYW2
Chromosome Location : 3p21.31
Pathway : Lysine degradation
Function : DNA binding; histone-lysine N-methyltransferase activity; methyltransferase activity; oxidoreductase activity; protein binding; transferase activity; transition metal ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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