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Recombinant Human TREM1, His-tagged

Cat.No. : TREM1-30119TH
Product Overview : Recombinant fragment, corresponding to amino acids 21-200 of Human TREM1 with an amino-terminal hexahistidine tag; 180 amino acids, 20kDa.
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  • Gene Information
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Description : This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Conjugation : HIS
Source : E. coli
Tissue specificity : Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in norma
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 50% Glycerol, PBS
Storage : Store at -20°C. Stable for 12 months at -20°C
Sequence Similarities : Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Gene Name : TREM1 triggering receptor expressed on myeloid cells 1 [ Homo sapiens ]
Official Symbol : TREM1
Synonyms : TREM1; triggering receptor expressed on myeloid cells 1; CD354; TREM 1;
Gene ID : 54210
mRNA Refseq : NM_001242589
Protein Refseq : NP_001229518
MIM : 605085
Uniprot ID : Q9NP99
Chromosome Location : 6p21.1
Pathway : Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem;
Function : receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Does TREM1 protein have antimicrobial effects? 11/03/2019

TREM1 protein can enhance inflammatory response during infection, but its specific relationship with antibacterial effect still needs further study.

What is the role of TREM1 protein in the treatment of lung diseases? 08/25/2019

High expression of the TREM1 protein in lung disease can trigger an excessive inflammatory response, and controlling its activity may help reduce the symptoms and inflammatory damage of lung disease.

How is the TREM1 protein related to bacterial infections? 04/22/2019

When bacterial infection occurs, the expression of the TREM1 protein increases, which enhances the inflammatory response, which helps clear the infection and regulate the inflammatory process.

What immune response is the TREM1 protein involved in? 03/20/2019

TREM1 protein is involved in immune response processes such as macrophage activation, release of inflammatory mediators, and recruitment and regulation of immune cells.

What are the implications of the study of TREM1 protein for the treatment of inflammatory diseases? 02/04/2019

The study of TREM1 protein helps to understand the regulatory mechanism of inflammatory response and provide new targets and strategies for the treatment of inflammatory diseases.

Does the TREM1 protein have the potential to predict and monitor disease progression? 01/12/2019

High expression of the TREM1 protein is associated with the development and prognosis of certain diseases and can therefore serve as a biomarker for predicting and monitoring disease progression.

Customer Reviews (3)

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Reviews
05/19/2022

    The exceptional stability of TREM1 makes it an invaluable tool for a wide range of applications.

    01/18/2020

      Manufacturer's commitment to environmental sustainability is evident in its production processes, using green and renewable resources.

      10/06/2019

        TREM1 has a short half-life, making it more effective and less likely to cause side effects compared to other similar proteins.

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