Recombinant Human TYRO3

• Cat.No.: TYRO3-31545TH
• Product Overview: Recombinant Human TYRO3 Fragment expressed by Baculovirus in Sf9 cells using an N terminal enzyme tag.

Specification

• Description: The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.
• Tissue specificity: Abundant in the brain and lower levels in other tissues.
• Biological activity: Specific activity: 154 nmol/min/mg.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.Contains 2 fibronectin type-III domains.Contains 2 Ig-like C2-type (immunoglobulin-like) domains.Contains 1 protein kinase domain.

Gene Information

• Gene Name: TYRO3 TYRO3 protein tyrosine kinase [ Homo sapiens ]
• Official Symbol: TYRO3
• Synonyms: TYRO3; TYRO3 protein tyrosine kinase; RSE; tyrosine-protein kinase receptor TYRO3; Brt; Dtk; Sky; Tif
• Gene ID: 7301
• mRNA Refseq: NM_006293
• Protein Refseq: NP_006284
• MIM: 600341
• Uniprot ID: Q06418
• Chromosome Location: 15q15.1-q21.1
• Function: ATP binding; nucleotide binding; phosphatidylinositol 3-kinase binding; protein heterodimerization activity; receptor activity