Recombinant Human UBE2D3, His-tagged
Cat.No. : | UBE2D3-30044TH |
Product Overview : | Recombinant full length Human UBE2D3, isoform 3 with an N terminal His tag mwt: 19.1 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. |
Protein length : | 149 amino acids |
Conjugation : | HIS |
Molecular Weight : | 19.100kDa inclusive of tags |
Source : | E. coli |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | pH: 8.00Constituents:0.32% Tris HCl, 40% Glycerol, 0.88% Sodium chloride, 0.02% DTT |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHMLSNR KCLSKELSDLARDPPAQCSAGPVGD DMFHWQATIMGPNDSPYQGGVFFLT IHFPTDYPFKPPKVAFTTRIYHPNI NSNGSICLDILRSQWSPALTISKVL LSICSLLCDPNPDDPLVPEIARIYK TDRDKYNRISREWTQKYAM |
Sequence Similarities : | Belongs to the ubiquitin-conjugating enzyme family. |
Gene Name : | UBE2D3 ubiquitin-conjugating enzyme E2D 3 [ Homo sapiens ] |
Official Symbol : | UBE2D3 |
Synonyms : | UBE2D3; ubiquitin-conjugating enzyme E2D 3; ubiquitin conjugating enzyme E2D 3 (homologous to yeast UBC4/5) , ubiquitin conjugating enzyme E2D 3 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2 D3; UbcH5C; |
Gene ID : | 7323 |
mRNA Refseq : | NM_003340 |
Protein Refseq : | NP_003331 |
MIM : | 602963 |
Uniprot ID : | P61077 |
Chromosome Location : | 4q24 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; Canonical NF-kappaB pathway, organism-specific biosystem; |
Function : | ATP binding; acid-amino acid ligase activity; ligase activity; nucleotide binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
UBE2D3-6053R | Recombinant Rat UBE2D3 Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2D3-816C | Recombinant Cynomolgus Monkey UBE2D3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ube2d3-6784M | Recombinant Mouse Ube2d3 Protein, Myc/DDK-tagged | +Inquiry |
UBE2D3-9824M | Recombinant Mouse UBE2D3 Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2D3-2004H | Recombinant Human UBE2D3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
UBE2D3-586HCL | Recombinant Human UBE2D3 293 Cell Lysate | +Inquiry |
UBE2D3-585HCL | Recombinant Human UBE2D3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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