Recombinant Human UCK2, His-tagged
Cat.No. : | UCK2-30101TH |
Product Overview : | Recombinant full length Human UCK2 (amino acids 1-261) with C terminal His tag; 269 amino acids with tag, MWt 30.3 kDa. |
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- Specification
- Gene Information
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Description : | This gene encodes a pyrimidine ribonucleoside kinase. The encoded protein (EC 2.7.1.48) catalyzes phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively. |
Protein length : | 261 amino acids |
Conjugation : | HIS |
Molecular Weight : | 30.300kDa inclusive of tags |
Source : | E. coli |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 2mM DTT, 100mM Sodium chloride, 1mM EDTA, 0.1mM PMSF, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MAGDSEQTLQNHQQPNGGEPFLIGV SGGTASGKSSVCAKIVQLLGQNEVD YRQKQVVILSQDSFYRVLTSEQKAK ALKGQFNFDHPDAFDNELILKTLKE ITEGKTVQIPVYDFVSHSRKEETVT VYPADVVLFEGILAFYSQEVRDLFQ MKLFVDTDADTRLSRRVLRDISERG RDLEQILSQYITFVKPAFEEFCLPT KKYADVIIPRGADNLVAINLIVQHI QDILNGGPSKRQTNGCLNGYTPSRK RQASESSSRPHLEHHHHHH |
Gene Name : | UCK2 uridine-cytidine kinase 2 [ Homo sapiens ] |
Official Symbol : | UCK2 |
Synonyms : | UCK2; uridine-cytidine kinase 2; UMPK, uridine monophosphate kinase; |
Gene ID : | 7371 |
mRNA Refseq : | NM_012474 |
Protein Refseq : | NP_036606 |
MIM : | 609329 |
Uniprot ID : | Q9BZX2 |
Chromosome Location : | 1p32 |
Pathway : | Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; Fluoropyrimidine Activity, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; |
Function : | ATP binding; kinase activity; nucleoside kinase activity; nucleotide binding; phosphotransferase activity, alcohol group as acceptor; |
Products Types
◆ Recombinant Protein | ||
Uck2-6823M | Recombinant Mouse Uck2 Protein, Myc/DDK-tagged | +Inquiry |
UCK2-4901R | Recombinant Rhesus Macaque UCK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
UCK2-2306H | Recombinant Human UCK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
UCK2-3953C | Recombinant Chicken UCK2 | +Inquiry |
UCK2-145H | Recombinant Human UCK2 protein, T7-tagged | +Inquiry |
◆ Lysates | ||
UCK2-531HCL | Recombinant Human UCK2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (5)
Ask a questionYes, UCK2 protein levels can be quantified in patient samples using techniques such as immunohistochemistry and ELISA for clinical assessment.
Certain genetic mutations in the UCK2 gene have been linked to altered UCK2 protein function, which may impact clinical outcomes in certain diseases.
Some studies have suggested a potential link between UCK2 protein and neurological disorders, although further research is needed to fully understand this association.
UCK2 protein has been implicated in liver diseases, particularly in the context of nucleoside analog metabolism and liver cell function.
UCK2 protein has been associated with drug resistance in cancer cells, particularly in the context of chemotherapy.
Customer Reviews (3)
Write a reviewI highly endorse the utilization of the UCK2 Protein for researchers seeking a superior protein solution that not only meets their experimental needs but also benefits from the exceptional technical support provided by the manufacturer.
Their expertise has proven instrumental in overcoming obstacles and has greatly contributed to the success of my research endeavors.
Their team of experts has been extremely helpful in addressing any concerns or queries I encountered during my experiments.
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