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Recombinant Human UCK2, His-tagged

Cat.No. : UCK2-30101TH
Product Overview : Recombinant full length Human UCK2 (amino acids 1-261) with C terminal His tag; 269 amino acids with tag, MWt 30.3 kDa.
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Description : This gene encodes a pyrimidine ribonucleoside kinase. The encoded protein (EC 2.7.1.48) catalyzes phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively.
Protein length : 261 amino acids
Conjugation : HIS
Molecular Weight : 30.300kDa inclusive of tags
Source : E. coli
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 2mM DTT, 100mM Sodium chloride, 1mM EDTA, 0.1mM PMSF, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MAGDSEQTLQNHQQPNGGEPFLIGV SGGTASGKSSVCAKIVQLLGQNEVD YRQKQVVILSQDSFYRVLTSEQKAK ALKGQFNFDHPDAFDNELILKTLKE ITEGKTVQIPVYDFVSHSRKEETVT VYPADVVLFEGILAFYSQEVRDLFQ MKLFVDTDADTRLSRRVLRDISERG RDLEQILSQYITFVKPAFEEFCLPT KKYADVIIPRGADNLVAINLIVQHI QDILNGGPSKRQTNGCLNGYTPSRK RQASESSSRPHLEHHHHHH
Gene Name : UCK2 uridine-cytidine kinase 2 [ Homo sapiens ]
Official Symbol : UCK2
Synonyms : UCK2; uridine-cytidine kinase 2; UMPK, uridine monophosphate kinase;
Gene ID : 7371
mRNA Refseq : NM_012474
Protein Refseq : NP_036606
MIM : 609329
Uniprot ID : Q9BZX2
Chromosome Location : 1p32
Pathway : Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; Fluoropyrimidine Activity, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;
Function : ATP binding; kinase activity; nucleoside kinase activity; nucleotide binding; phosphotransferase activity, alcohol group as acceptor;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Can UCK2 protein levels in patient samples be measured for clinical assessment? 12/04/2021

Yes, UCK2 protein levels can be quantified in patient samples using techniques such as immunohistochemistry and ELISA for clinical assessment.

Are there any genetic mutations associated with UCK2 protein that impact clinical outcomes? 05/15/2020

Certain genetic mutations in the UCK2 gene have been linked to altered UCK2 protein function, which may impact clinical outcomes in certain diseases.

Does UCK2 protein have any role in neurological disorders? 03/01/2019

Some studies have suggested a potential link between UCK2 protein and neurological disorders, although further research is needed to fully understand this association.

How is UCK2 protein involved in liver diseases? 03/31/2018

UCK2 protein has been implicated in liver diseases, particularly in the context of nucleoside analog metabolism and liver cell function.

What role does UCK2 protein play in drug resistance in cancer? 03/19/2016

UCK2 protein has been associated with drug resistance in cancer cells, particularly in the context of chemotherapy.

Customer Reviews (3)

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08/24/2022

    I highly endorse the utilization of the UCK2 Protein for researchers seeking a superior protein solution that not only meets their experimental needs but also benefits from the exceptional technical support provided by the manufacturer.

    10/09/2021

      Their expertise has proven instrumental in overcoming obstacles and has greatly contributed to the success of my research endeavors.

      05/07/2020

        Their team of experts has been extremely helpful in addressing any concerns or queries I encountered during my experiments.

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