Active Recombinant Mouse Tgfbr1 Protein, Fc-tagged
Cat.No. : | Tgfbr1-1777M |
Product Overview : | Recombinant mouse TGF-beta RI (Ala21-Glu121) & (Thr22-Glu121) with a Human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in Spodoptera frugiperda, Sf 21 (baculovirus). |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the transforming growth factor beta (TGF-beta) receptor family of proteins. These proteins comprise one component of the TGF-beta signaling pathway, which transduces extracellular signals into gene expression changes to regulate a wide range of cellular responses, including proliferation, migration, differentiation and apoptosis. Homozygous knockout mice for this gene exhibit impaired angiogenesis and embryonic lethality. Alternative splicing results in multiple transcript variants. |
Source : | Insect cell |
Species : | Mouse |
Tag : | Fc |
Form : | Disulfide-linked homodimer |
Bio-activity : | Measured by its binding ability in a functional ELISA. When Recombinant Rat Endoglin/CD105 Fc Chimera or Recombinant Mouse Endoglin/CD105 Fc Chimera is immobilized at 2 μg/mL (100 μL/well), the concentration of Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera that produces 50% of the optimal binding response is found to be approximately 0.25-1.25 μg/mL. |
Molecular Mass : | 37.5 kDa (monomer) |
N-terminal Sequence Analysis : | Ala21 & Thr22 |
Endotoxin : | <0.1 EU/μg of the protein by the LAL method. |
Purity : | >90% by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution : | Reconstitute at 500 μg/mL in sterile PBS. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | Tgfbr1 transforming growth factor, beta receptor I [ Mus musculus (house mouse) ] |
Official Symbol : | Tgfbr1 |
Synonyms : | Tgfbr1; transforming growth factor, beta receptor I; AL; Alk; ALK5; ESK2; Tbet; Alk-5; Tbeta; TGFR-1; TbetaRI; AU017191; TbetaR-I; TGF-beta receptor type-1; TGF-beta receptor type I; transforming growth factor-beta receptor type I; EC 2.7.11.30 |
Gene ID : | 21812 |
mRNA Refseq : | NM_009370 |
Protein Refseq : | NP_033396 |
UniProt ID : | Q64729 |
Products Types
◆ Recombinant Protein | ||
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TGFBR1-5523H | Recombinant Human Transforming Growth Factor, Beta Receptor 1 | +Inquiry |
Tgfbr1-6392M | Recombinant Mouse Tgfbr1 Protein, Myc/DDK-tagged | +Inquiry |
TGFBR1-1292H | Recombinant Human TGFBR1 Protein (T200-M503), His tagged | +Inquiry |
TGFBR1-701H | Recombinant Human TGFBR1 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
TGFBR1-001HCL | Recombinant Human TGFBR1 cell lysate | +Inquiry |
TGFBR1-2482HCL | Recombinant Human TGFBR1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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