Recombinant Human VEGFC, Fc-tagged

• Cat.No.: VEGFC-31451TH
• Product Overview: Recombinant full length human VEGFC expressed in modified human 293 cells; secreted disulfide linked antiparallel homodimer; 45-55kDa.

Specification

• Description: The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels.This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
• Conjugation: Fc
• Form: Lyophilised:It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial.Following reconstitution short-term storage at 4°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not reco
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Trehalose, 1% Human serum albumin
• Storage: Store at +4°C.
• Sequences of amino acids: TheoreticalSequence:FESGLDLSDAEPDAGEAT AYASKDLEEQLRSVSSVDELMTVLY PEYWKMYKCQLRK GGWQHNREQANLNSRTEETIKFAAA HYNTEILKSIDNEWRKTQCMPREVC IDVGKEFGVATNTFFKPPCVSVYRC GGC CNSEGLQCMNTSTSYLSKTLFEITV PLSQGPKPVTISF ANHTSCRCMSKLDVYRQVHSIIRRD isulfide bonded to:SLPATLPQCQAANKTCPTNYMWNNH ICRCLAQEDF MFSSDAGDDSTDGFHDICGPNKELD EETCQCVCRAGLR PASCGPHKELDRNSCQCVCKNKLFP SQCGANREFDENT CQCVCKRTCPRNQPLNPGKCACECT ESPQKCLLKGKKF HHQTCSCYRRPCTNRQKACEPGFSY SEEVCRCVPSYWKRPQMSNote: N-terminal sequences confirmed by Edman sequencing.

Gene Information

• Gene Name: VEGFC vascular endothelial growth factor C [ Homo sapiens ]
• Official Symbol: VEGFC
• Synonyms: VEGFC; vascular endothelial growth factor C; VRP
• Gene ID: 7424
• mRNA Refseq: NM_005429
• Protein Refseq: NP_005420
• MIM: 601528
• Uniprot ID: P49767
• Chromosome Location: 4q34.3
• Pathway: Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem
• Function: chemoattractant activity; growth factor activity; protein binding; vascular endothelial growth factor receptor 3 binding