Recombinant Human XCL1
Cat.No. : | XCL1-27983TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 23-114 of Human Lymphotactin, 92 amino acids, 10kDa. |
- Specification
- Gene Information
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Description : | This gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. |
Source : | E. coli |
Tissue specificity : | Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine. |
Biological activity : | Biological Activity:The Biological activity is calculated by its ability to chemoattract human T cells at 10.0-100.0 ng/ml. |
Form : | Lyophilised:Reconstitute in sterile 18MO-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions.Upon reconstitution XCL1-27983TH should be stored at 4°C between 2-7 days and for future use below -18°C. For long term st |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: ddH20 |
Storage : | Store at -20°C or lower.Aliquot to avoid repeated freezing and thawing. |
Sequences of amino acids : | The sequence of the first five N-terminal amino acids was determined and was found to be Gln-Ser-Glu-Val-Ser. |
Sequence Similarities : | Belongs to the intercrine gamma family. |
Gene Name : | XCL1 chemokine (C motif) ligand 1 [ Homo sapiens ] |
Official Symbol : | XCL1 |
Synonyms : | XCL1; chemokine (C motif) ligand 1; LTN, SCYC1, small inducible cytokine subfamily C, member 1 (lymphotactin); lymphotactin; ATAC; LPTN; SCM 1; SCM 1a; |
Gene ID : | 6375 |
mRNA Refseq : | NM_002995 |
Protein Refseq : | NP_002986 |
MIM : | 600250 |
Uniprot ID : | P47992 |
Chromosome Location : | 1q24.2 |
Pathway : | Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; |
Function : | chemokine activity; chemokine receptor binding; chemokine receptor binding; protein homodimerization activity; |
Products Types
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XCL1-084X | Active Recombinant Human XCL1 Protein (92 aa) | +Inquiry |
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◆ Lysates | ||
XCL1-452CCL | Recombinant Cynomolgus XCL1 cell lysate | +Inquiry |
XCL1-466HCL | Recombinant Human XCL1 cell lysate | +Inquiry |
XCL1-480MCL | Recombinant Mouse XCL1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionXCL1 expression is regulated by various stimuli, including inflammatory signals. Understanding how these stimuli modulate XCL1 secretion provides insights into its dynamic role in immune activation.
XCL1 influences the differentiation and function of dendritic cells, affecting the priming and activation of T cells. Understanding these processes has implications for modulating adaptive immune responses in various contexts.
XCL1 is involved in the formation of immune synapses between dendritic cells and T cells. Molecular events include the coordinated expression of adhesion molecules and the release of other signaling molecules.
XCL1 binds to its receptor XCR1, initiating intracellular signaling cascades. This interaction influences immune cell function by directing the migration and activation of specific immune cell subsets.
XCL1 is implicated in the host immune response to viral infections. Its role in recruiting and activating immune cells may influence the outcome of infections, impacting viral clearance and immune memory.
Customer Reviews (3)
Write a reviewConsistent high quality, responsive customer service, and seamless delivery
Commendable product quality, professional customer service, and punctual delivery.
Outstanding product quality, swift delivery, and helpful customer service. Highly recommend!
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