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Recombinant Human YWHAH, His-tagged

Cat.No. : YWHAH-26005TH
Product Overview : Recombinant full length protein corresponding to amino acids 1 - 246 of Human 14-3-3 eta; with an N-terminal his tag; predicted MWt 31.7 kDa inclusive of tag.Residue M35 of the fusion protein is equivalent to M1 of the native protein. The His(6) tag is lo
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  • Gene Information
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Description : This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5 UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.
Protein length : 246 amino acids
Conjugation : HIS
Molecular Weight : 31.700kDa inclusive of tags
Source : E. coli
Tissue specificity : Expressed mainly in the brain and present in other tissues albeit at lower levels.
Form : Liquid
Purity : Purified via His tag
Storage buffer : pH: 7.50Constituents:0.6% HEPES, 0.02% DTT, 50% Glycerol, 0.012% Benzamidine, 0.003% PMSF
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRGSMGDREQ LLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLS VAYKNVVGARRSSWRVISSIEQKTMADGNEKKLEKVKAYR EKIEKELETVCNDVLSLLDKFLIKNCNDFQYESKVFYLKM KGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQ PTHPIRLGLALNFSVFYYEIQNAPEQACLLAKQAFDDAIA ELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDEEAGEGN
Sequence Similarities : Belongs to the 14-3-3 family.
Gene Name : YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide [ Homo sapiens ]
Official Symbol : YWHAH
Synonyms : YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; YWHA1; 14-3-3 protein eta; 14 3 3 eta;
Gene ID : 7533
mRNA Refseq : NM_003405
Protein Refseq : NP_003396
MIM : 113508
Uniprot ID : Q04917
Chromosome Location : 22q12.1-q13.1
Pathway : Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem;
Function : actin binding; enzyme binding; glucocorticoid receptor binding; insulin-like growth factor receptor binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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