Recombinant Human UBA1, GST-tagged
Cat.No. : | UBA1-476H |
Product Overview : | Recombinant Human UBA1, amino acids 2-end with N-terminal FLAG tag expressed inSf9expression system. MW = 118kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | UBA1-476H |
Description : | Ubiquitin-like modifier activating enzyme 1, also known as UBA1, is an enzyme which in humans is encoded by the UBA1 gene. In non-primates, the gene UBE1, rather than the SRY gene, is commonly used for sexual determination. |
Source : | Sf9. |
Purity : | >65%. |
Application : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Formulated In : | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT. |
Stability : | >6 months at –80°C. |
Gene Name : | UBA1 ubiquitin-like modifier activating enzyme 1 [ Homo sapiens ] |
Synonyms : | UBA1; ubiquitin-like modifier activating enzyme 1; A1S9; A1ST; GXP1; UBE1; A1S9T; AMCX1; SMAX2; UBA1A; UBE1X; MGC4781; UBA1, ubiquitin-activating enzyme E1 homolog A; A1S9T and BN75 temperature sensitivity complementing; ubiquitin-activating enzyme E1; EC 6.3.2.19 |
Gene ID : | 7317 |
mRNA Refseq : | NM_003334 |
Protein Refseq : | NP_003325 |
MIM : | 314370 |
UniProt ID : | P22314 |
Chromosome Location : | Xp11.23 |
Pathway : | Parkinson"s disease; Ubiquitin mediated proteolysis |
Function : | ATP binding; ligase activity; nucleotide binding; small protein activating enzyme activity; protein binding |
Products Types
◆ Recombinant Protein | ||
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UBA1-337H | Recombinant Human UBA1 Protein, His-tagged | +Inquiry |
Uba1-6764M | Recombinant Mouse Uba1 Protein, Myc/DDK-tagged | +Inquiry |
UBA1-7333H | Recombinant Human UBA1 protein(Ser2-Arg1058), His&GST-tagged | +Inquiry |
◆ Lysates | ||
UBA1-420HCL | Recombinant Human UBA1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionSome early-phase clinical trials are exploring UBA1 as a potential target in the context of ALS and cancer.
Targeting UBA1 with small molecules or gene therapy may provide a potential avenue for treating UBA1-related diseases.
UBA1 activates ubiquitin, a small protein that tags other proteins for degradation by the proteasome.
UBA1 dysfunction has been linked to neurodegenerative diseases like amyotrophic lateral sclerosis (ALS) and certain types of cancer.
Research suggests that altered UBA1 levels in the cerebrospinal fluid may be a potential biomarker for ALS diagnosis.
Customer Reviews (3)
Write a reviewThe UBA1 protein comes highly recommended for its outstanding performance in various experimental applications.
In ELISA assays, it has consistently exhibited exceptional reliability and accuracy, providing precise and reproducible results.
Their prompt and knowledgeable guidance has been instrumental in effectively addressing my queries and optimizing the utilization of the UBA1 protein in my studies.
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