Native Bothrops atrox snake venom Batroxobin Protein
Cat.No. : | Batroxobin-99 |
Product Overview : | Batroxobin is a serin protease that reduces fibronogen levels and is originally extracted from snake venom of Bothrops Atrox. |
- Specification
- Gene Information
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Description : | Batroxobin is used in defibrinogenation and thrombolysis and also has an effect on c-fos gene and growth factor. Batroxobin can efficiently restrain proliferation of VSMCs, by blocking the release and uptake of Ca2+, thus influencing [Ca2+]i. Batroxobin converts fibrinogen to fibrin through the restricted release of fibrinopeptide-A from fibrinogen to promote blood to clot. Unlike thrombin, it is not affected by heparin and hirudin. |
Source : | Snake venom |
Species : | Bothrops atrox |
Form : | Sterile Filtered white lyophilized powder. |
Molecular Mass : | 43 kDa |
Unit Definition : | 100BU [Batroxobin Units]=1mg. |
Storage : | Batroxobin although stable at room temperature for 3 weeks, should be stored below -18 centigrade. Upon reconstitution Batroxobin should be stored at 4 centigrade between 2-7 days and for future use below -18 centigrade. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Storage Buffer : | The Batroxobin protein was lyophilized from a concentrated (1 mg/mL) solution with no additives. |
Reconstitution : | It is recommended to reconstitute the lyophilized Batroxobin in sterile 18M-cm H2O not less than 100 μg/mL, which can then be further diluted to other aqueous solutions. |
Synonyms : | Thrombin-like enzyme batroxobin; EC 3.4.21.74; BX; Bothrops atrox serine proteinase; Venombin-A; Defibrase; Reptilase; Batroxobin |
Publication : |
Contributions of thrombin targets to tissue factor‐dependent metastasis in hyperthrombotic mice (2013)
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Synonyms : | Thrombin-like enzyme batroxobin; EC 3.4.21.74; BX; Bothrops atrox serine proteinase; Venombin-A; Defibrase; Reptilase; Batroxobin |
Products Types
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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