Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human 6-Pyruvoyltetrahydropterin Synthase, His-tagged

Cat.No. : PTS-492H
Product Overview : Recombinant human PTS fused to His-tag at N-terminus was expressed in E.coli and purified by using conventional chromatography techniques. MW = 18.5 kDa (165aa).
  • Specification
  • Gene Information
  • Related Products
Cat. No. : PTS-492H
Description : 6-Pyruvoyltetrahydropterin synthase (PTS), also known as PTPS, belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 20% glycerol.
Purity : > 90% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MSTEGGGRRC QAQVSRRISF SASHRLYSKF LSDEENLKLF GKCNNPNGHG HNYKVVVTVH GEIDPATGMVMNLADLKKYM EEAIMQPLDH KNLDMDVPYF ADVVSTTENV AVYIWDNLQK VLPVGVLYKV KVYETDNNIV VYKGE.
Storage : can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : PTS 6-pyruvoyltetrahydropterin synthase [ Homo sapiens ]
Synonyms : 6-pyruvoyltetrahydropterin synthase; PTPS; FLJ97081; PTS; PTP synthase; 6-pyruvoyl tetrahydrobiopterin synthase;EC 4.2.3.12
Gene ID : 5805
mRNA Refseq : NM_000317
Protein Refseq : NP_000308
MIM : 612719
UniProt ID : Q03393
Chromosome Location : 11q22.3-q23.3
Pathway : Folate biosynthesis; Metabolic pathways
Function : 6-pyruvoyltetrahydropterin synthase activity; identical protein binding; lyase activity; metal ion binding; protein homodimerization activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All PTS Products

Required fields are marked with *

My Review for All PTS Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends