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Recombinant Human MCFD2, T7-tagged

Cat.No. : MCFD2-1836H
Product Overview : Recombinant human MCFD2 fused to T7-tag at N-terminus was expressed inE.coliand purified by using conventional chromatography techniques.MW = 15.1 kDa (136aa).
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  • Gene Information
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Cat. No. : MCFD2-1836H
Description : Multiple coagulation factor deficiency 2 (MCFD2), also known as SDNSF. This is expressed by neural stem/progenitor cells of the hippocampus, and localized to region where neurogenesis persists throughout life. It has been found to prevent NSC cell death and to maintain stem cell characteristics. This protein forms a complex with LAMN1 that facilitates the transport of coagulation factors V and VIII from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment. Mutations in the MCFD2 gene may cause Factor V and Factor VIII combined deficiency.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer (pH7.5) containing 100mM NaCl, 10% glycerol.
Purity : > 90% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MASMTGGQQM GRGSHMEEPA ASFSQPGSMG LDKNTVHDQE HIMEHLEGVI NKPEAEMSPQ ELQLHYFKMH DYDGNNLLDG LELSTAITHVHKEEGSEQAP LMSEDELINI IDGVLRDDDK NNDGYIDYAE FAKSLQ.
Storage : can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : MCFD2 multiple coagulation factor deficiency 2 [ Homo sapiens ]
Synonyms : multiple coagulation factor deficiency 2; F5F8D; SDNSF; LMAN1IP; DKFZp686G21263; MCFD2; neural stem cell derived neuronal survival protein; OTTHUMP00000203115; multiple coagulation factor deficiency protein 2; OTTHUMP00000203117; OTTHUMP00000203119; OTTHUMP00000203118; Neural stem cell-derived neuronal survival protein
Gene ID : 90411
mRNA Refseq : NM_001171506
Protein Refseq : NP_001164977
MIM : 607788
UniProt ID : Q8NI22
Chromosome Location : 2p21
Function : calcium ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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