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Active Recombinant Mouse Dcn protein, His-tagged

Cat.No. : Dcn-1887M
Product Overview : Recombinant Mouse Dcn(Gly17-­Lys354 & Asp31-­Lys354) fused with His tag at C-terminal was expressed in NS0.
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  • Gene Information
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Source : Mammalian cells
Species : Mouse
Tag : His
Predicted N Terminal : Gly17 & Asp31
Form : Lyophilized from a 0.2 μm filtered solution in PBS.
Bio-activity : 5 µg/mL of Recombinant Mouse Decorin can significantly delay the rate of collagen fibrillogenesis.
Molecular Mass : Predicted Molecular Mass: 39 kDa;SDS-PAGE: 40-45 kDa, reducing conditions
Endotoxin : <0.10 EU per 1 μg of the protein by the LAL method.
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Stability : Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : Reconstitute at 100 μg/mL in sterile PBS.
Gene Name : Dcn decorin [ Mus musculus ]
Official Symbol : Dcn
Synonyms : DCN; decorin; bone proteoglycan II; DC; PG40; PGII; PGS2; mDcn; DSPG2; SLRR1B;
Gene ID : 13179
mRNA Refseq : NM_001190451
Protein Refseq : NP_001177380
UniProt ID : P28654
Chromosome Location : 10 C3; 10 50.27 cM
Pathway : TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem;
Function : collagen binding; extracellular matrix binding; glycosaminoglycan binding; protein N-terminus binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the effect of targeted DCN delivery on tumor growth in a mouse model of breast cancer? 07/10/2022

Targeted DCN delivery in breast cancer models reduces tumor growth.

How does DCN modulate TGF-β signaling at the molecular level? 05/06/2022

DCN modulates TGF-β signaling, affecting fibrosis and cancer development.

How do variations in the glycosaminoglycan chains attached to DCN influence its interaction with growth factors? 12/11/2021

Variations in DCN's glycosaminoglycan chains influence its growth factor interactions.

What are the cellular and molecular consequences of DCN gene silencing in fibroblasts? 12/07/2021

DCN gene silencing in fibroblasts alters extracellular matrix production and cell mobility.

How do mechanical forces influence the function and localization of DCN in the cardiac extracellular matrix? 04/30/2021

Mechanical forces impact DCN's role in cardiac matrix organization and cell signaling.

Which proteins are differentially expressed in cells overexpressing DCN compared to control cells? 10/14/2019

Overexpression of DCN changes protein expression related to cell growth and matrix interactions.

What is the detailed three-dimensional structure of DCN when bound to collagen? 07/27/2018

DCN bound to collagen reveals binding sites essential for collagen structure.

Customer Reviews (3)

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Reviews
03/11/2020

    Excellent support for protein purification. Highly recommend this service.

    11/01/2019

      Efficient protein expression, quick turnaround time, and reliable results.

      10/14/2019

        Outstanding antibody validation; trustworthy for protein-protein interaction studies.

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