| Cat. No. | CABT-48626MH |
| Antigen Description | CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette receptor. |
| Product Overview | MOUSE ANTI HUMAN CD2 Monoclonal Antibody,LOW ENDOTOXIN |
| Immunogen | Normal human peripheral blood lymphocytes. |
| Isotype | IgG2b |
| Specificity | CABT-48626MH is a single chain transmembrane glycoprotein of 50kD, expressed by T cells, NK cells and thymocytes.CD2 is a receptor for CD58 (LFA-3), and is important in mediating the interaction between T cells and target cells or antigen presenting cells. MCA1194XZ inhibits NK cell mediated cytotoxicity, and ConA and PHA mediated blast transformation. |
| Application | Flow Cytometry Immunohistology - Frozen Immunoprecipitation Functional Assays |
| Form | Purified IgG - liquid |
| Storage Buffer | Store at -20oC only.This product should be stored undiluted.Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Buffer Stabilisers | Buffer Solution:Phosphate buffered saline
Preservative Stabilisers:None present |
| Reactivity | Human |
| Preparation | Purified IgG prepared by affinity chromatography on Protein G |
| Shelf Life | 18 months from date of despatch. |
| Clone | MU3 |
| Host | Mouse |
| Antigen Gene Information | Gene Name | CD2 CD2 molecule [ Homo sapiens ] |
| Official symbol | CD2 |
| Synonyms | CD2; T11; SRBC; FLJ46032; T-cell surface antigen CD2; CD2 molecule; CD2 antigen (p50), sheep red blood cell receptor, SRBC |
| GeneId | 914 |
| mRNA Refseq | NM_001767 |
| Protein Refseq | NP_00175 |
| MIM | 186990 |
| Uniprot ID | P06729 |
| Chromosome Location | 1p13 |
| Pathway | Cell adhesion molecules (CAMs), organism-specific biosystem |
| Function | eukaryotic cell surface binding; protein binding; protein homodimerization activity; receptor activity |
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