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Active Recombinant Human Platelet-derived Growth Factor AA

Cat.No. : PDGFA-375H
Product Overview : Recombinant human Xeno-free PDGFaa is expressed inhuman 293 cellsas a mixture of pro-dimers, pro-mature and mature dimers with an apparent molecular mass of 35 to 45 kDa.
  • Specification
  • Gene Information
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Cat. No. : PDGFA-375H
Description : Platelet-derived growth factor subunit A is a protein that in humans is encoded by the PDGFA gene. The protein encoded by this gene is a member of the platelet-derived growth factor family. The cytokine is produced in a human cell expression system with serum free, chemically defined media.
Source : Human 293 cells.
Activity : 200 to 1000 ng/mL ED50.
Purity : >95%.
Endotoxin : Endotoxin-free.
Purity Confirmation : The protein was resolved by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.
Activity Assay : The specific activity was determined by the dose-dependent stimulation of the proliferation of 3T3 cells.
Pathways : Focal adhesion; Gap junction; Glioma; MAPK signaling pathway; Melanoma; Prostate cancer; Regulation of actin cytoskeleton; Hemostasis
Gene Name : PDGFA platelet-derived growth factor alpha polypeptide [ Homo sapiens ]
Synonyms : platelet-derived growth factor alpha polypeptide; PDGF1; PDGF-A; PDGFA; platelet-derived growth factor alpha; PDGF A-chain; platelet-derived growth factor alpha chain; platelet-derived growth factor alpha isoform 2 preproprotein; PDGF1; PDGF subunit A; Platelet-derived growth factor A chain; platelet-derived growth factor alpha polypeptide
Gene ID : 5154
mRNA Refseq : NM_002607
Protein Refseq : NP_002598
MIM : 173430
UniProt ID : P04085
Chromosome Location : 7p22
Function : cell surface binding; collagen binding; growth factor activity; platelet-derived growth factor binding; platelet-derived growth factor receptor binding; contributes_to platelet-derived growth factor receptor binding; platelet-derived growth factor receptor binding; protein heterodimerization activity; protein homodimerization activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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