Active Recombinant Human Transforming Growth Factor, Beta 3
| Cat.No. : |
TGFB3-376H |
| Product Overview : |
Recombinant human Xeno-free TGF beta 3 is expressed fromhuman 293 cellsas a mature disulfide-linked homodimer with apparent molecular mass of 25 kDa. |
- Specification
- Gene Information
- Related Products
| Cat. No. : |
TGFB3-376H |
| Description : |
Transforming growth factor beta-3 is a protein that in humans is encoded by the TGFB3 gene. It has been shown to interact with TGF beta receptor 2. This cytokine is produced in a human cell expression system with serum-free, chemically defined media. The cytokine is greater than 95% pure. |
| Source : |
Human 293 cells. |
| Activity : |
0.1 to 0.5 ng/mL ED50. |
| Purity : |
>95%. |
| Endotoxin : |
Endotoxin-free. |
| Purity Confirmation : |
The protein was resolved by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue. |
| Activity Assay : |
The specific activity was determined by the dose-dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2). |
| Pathways : |
Cell cycle; Chronic myeloid leukemia; Colorectal cancer; Cytokine-cytokine receptor interaction; Hypertrophic cardiomyopathy (HCM); MAPK signaling pathway; Pancreatic cancer;Pathways in cancer; Renal cell carcinoma; TGF-beta signaling pathway |
| Gene Name : |
TGFB3 transforming growth factor, beta 3 [ Homo sapiens ] |
| Synonyms : |
Transforming Growth Factor-beta3; TGFB3; ARVD; FLJ16571; TGF-beta3; transforming growth factor, beta 3 |
| Gene ID : |
7043 |
| mRNA Refseq : |
NM_003239 |
| Protein Refseq : |
NP_003230 |
| MIM : |
190230 |
| UniProt ID : |
P10600 |
| Chromosome Location : |
14q24 |
| Function : |
Growth factor activity; Identical protein binding; Protein heterodimerization activity; Transforming growth factor beta binding; Type I transforming growth factor beta receptor binding; Type II transforming growth factor beta receptor binding |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
