Recombinant Human Arachidonate 5-lipoxygenase 1

• Cat.No.: ALOX5-578H
• Product Overview: Recombinant Human Arachidonate 5-lipoxygenase 1 is expressed ina Baculovirus overexpression system inSf21 cells. The molecular weight of the recombinant ALOX5 is 78 kDa.

Specification

• Cat. No.: ALOX5-578H.
• Description: Arachidonate 5-lipoxygenase (5-lipoxygenase, 5-LO or Alox5) is a member of the lipoxygenase family of enzymes. It transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases. This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid.
• Source: Sf21 cells.
• Purity: cell lysate 16,000 x g supernatant.
• Formulation: A solution in 100 mM Tris, pH 8.0, containing 2 mM EGTA.
• Storage: -80℃, 6 months.

Gene Information

• Gene Name: ALOX5 arachidonate 5-lipoxygenase [ Homo sapiens ]
• Synonyms: arachidonate 5-lipoxygenase; ALOX5; 5-LO; 5LPG; LOG5; 5-LOX; MGC163204; leukotriene A4 synthase; arachidonic acid 5-lipoxygenase
• Gene ID: 240
• mRNA Refseq: NM_000698
• Protein Refseq: NP_000689
• MIM: 152390
• UniProt ID: P09917
• Chromosome Location: 8p12
• Pathway: Arachidonic acid metabolism; Metabolic pathwaysy
• Function: arachidonate 5-lipoxygenase activity; iron ion binding; lipoxygenase activity; metal ion binding; oxidoreductase activity;protein binding