Recombinant Human Adenosylmethionine Decarboxylase 1, T7-tagged

• Cat.No.: AMD1-577H
• Product Overview: Recombinant Human adenosylmethionine decarboxylase 1 is expressed inE. coli.The molecular weight of the recombinant Human AMD1 is 38.3 kDaand contains 334 amino acids. AMD1 contains T7 tag at N-terminus.

Specification

• Cat. No.: AMD1-577H.
• Description: AMD1 catalyzes the removal of the carboxylate group of S-adenosylmethionine in the polyamine biosynthesis pathway. Adenosylmethionine decarboxylase is an enzyme which catalyzes the conversion of S-Adenosyl methionineto S-adenosyl-5"-3-methylpropylamine. This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified.
• Source: E. coli.
• Purity: Greater than 95.0% as determined by SDS-PAGE.
• Physical Appearance: Sterile Filtered clear solution.
• Formulation: AdoMetDC at 0.1mg/ml, 10mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN3.
• Storage: S-Adenosylmethionine Decarboxylase although stable at 14℃ for 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Gene Information

• Gene Name: AMD1 adenosylmethionine decarboxylase 1 [ Homo sapiens ]
• Synonyms: adenosylmethionine decarboxylase 1; AMD1; AMD; SAMDC; ADOMETDC; FLJ26964; DKFZp313L1234; S-adenosylmethionine decarboxylase 1; S-adenosylmethionine decarboxylase 1
• Gene ID: 262
• mRNA Refseq: NM_001033059
• Protein Refseq: NP_001028231
• MIM: 180980
• UniProt ID: Q5VXN4
• Chromosome Location: 6q21-q22
• Pathway: Arginine and proline metabolism; Cysteine and methionine metabolism; Metabolic pathways; Metabolism of amino acids and derivatives; Metabolism of polyamines
• Function: lyase activity; Adenosylmethionine decarboxylase activity; adenosylmethionine decarboxylase activity