Recombinant Human Melan-A

• Cat.No.: MLANA-2043H
• Product Overview: Recombinant human full length MART-1 protein was expressed inE.coli.

Specification

• Cat. No.: MLANA-2043H
• Description: MART-1 or MELAN-A is newly identified melanocyte differentiation antigen recognized by autologous T lymphocytes. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, Tyrosinase, gp100, gp75, BAGE-1 and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum.
• Source: E. coli.
• Purity: > 90% by SDS-PAGE.
• Supplied: 250 ng in 50 ml 50 mM Tris-HCl pH 7.0 buffer containing 14 mM b-mercaptoethanol, 1 mM benzamidine, 0.1 mM phenylmethanesulfonyl fluoride, 1 mM EDTA and 0.1% Brij-35 and 10% glycerol.
• Application And Suggested Dilutions: •ELISA •Inhibition Assays •Western Blotting.
• Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 18kDa.
• Presentation: 20 µl purified human MART-1 protein at 100 µg/ml in 50 mM Tris-Acetate, pH 7.5, 1 mM EDTA and 20% Glycerol.
• Storage & Stability: Store vial at -20 °C to -80 °C. When stored at the recommended temperature, this protein is stable for 12 months.

Gene Information

• Gene Name: MLANA melan-A [ Homo sapiens ]
• Synonyms: melan-A; MART1; MART-1; MLANA; melanoma antigen recognized by T-cells 1; antigen LB39-AA; antigen SK29-AA; protein Melan-A;melan-A; Melan-A protein; Antigen SK29-AA; Antigen LB39-AA; OTTHUMP00000021038; OTTHUMP00000021037
• Gene ID: 2315
• mRNA Refseq: NM_005511
• Protein Refseq: NP_005502
• MIM: 605513
• UniProt ID: Q16655
• Chromosome Location: 9p24.1
• Function: protein binding