Recombinant Human TNFRSF6B, Fc Chimera
Cat.No. : | TNFRSF6B-2078H |
Product Overview : | Recombinant Human TNFRSF6B is produced inHEK 293 Cells.The extracellular domain of human DcR3 (decoy receptor 3) (aa 1-246) is fused to the Fc portion of human IgG1. MW=58kDa. |
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- Gene Information
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Cat. No. : | TNFRSF6B-2078H |
Description : | This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5" UTR, have been observed for this gene. |
Source : | HEK 293 Cells. |
Concentration : | 1mg/ml after reconstitution. |
Formulation : | Lyophilized. Contains PBS. |
Endotoxin Content : | <0.1EU/µg purified protein (LAL test; Bio Whittaker). |
Reconstitution : | Reconstitute with 50µl sterile water. |
Specificity : | Binds human LIGHT. Does not bind human FasL. |
Application : | Detection of human LIGHT and TL1A (VEGI) in combination with PAb to human IgG1. |
Purity : | ≥90% (SDS-PAGE). |
Storage : | Stable for at least 6 months after receipt when stored at -20°C. Avoid freeze/thaw cycles. |
Gene Name : | TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy [ Homo sapiens ] |
Synonyms : | TNFRSF6B; tumor necrosis factor receptor superfamily, member 6b, decoy; M68; TR6; DCR3; DJ583P15.1.1; TNFRSF6B; tumor necrosis factor receptor superfamily member 6B; decoy receptor 3; decoy receptor for Fas ligand |
Gene ID : | 8771 |
mRNA Refseq : | NM_003823 |
Protein Refseq : | NP_003814 |
MIM : | 603361 |
UniProt ID : | O95407 |
Chromosome Location : | 20q13.3 |
Pathway : | Cytokine-cytokine receptor interaction |
Function : | protein binding; receptor activity |
Products Types
◆ Recombinant Protein | ||
TNFRSF6B-432H | Active Recombinant Human TNFRSF6B protein(Met1-His300), hFc-tagged | +Inquiry |
TNFRSF6B-814H | Recombinant Human TNFRSF6B Protein, Fc-tagged | +Inquiry |
TNFRSF6B-333H | Recombinant Human tumor necrosis factor receptor superfamily, member 6b, decoy, His-tagged | +Inquiry |
TNFRSF6B-1083H | Active Recombinant Human TNFRSF6B Protein, Fc Chimera | +Inquiry |
TNFRSF6B-253C | Active Recombinant Cynomolgus TNFRSF6B protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
TNFRSF6B-001HCL | Recombinant Human TNFRSF6B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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