Recombinant Human Ectodysplasin A, FLAG-tagged
Cat.No. : | EDA-2082H |
Product Overview : | Recombinant Human EDA is produced inHEK 293 Cells. The extracellular domain of human EDA-A2 (ectodysplasin-A2) (aa 245-391) is fused at the N-terminus to a linker peptide (10 aa) and a FLAG-tag. MW=28kDa (SDS-PAGE). |
- Specification
- Gene Information
- Related Products
Cat. No. : | EDA-2082H |
Description : | EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. |
Source : | HEK 293 Cells. |
Purity : | ≥90% (SDS-PAGE). |
Concentration : | 0.1mg/ml after reconstitution. |
Formulation : | Lyophilized. Contains PBS. |
Endotoxin Content : | <0.1EU/µg purified protein (LAL test; Bio Whittaker). |
Reconstitution : | Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum. |
Specificity : | Binds to human XEDAR (X-linked ectodysplasin-A2 receptor). |
Stability : | Stable for at least 6 months after receipt when stored at -20°C. |
Gene Name : | EDA ectodysplasin A [ Homo sapiens ] |
Synonyms : | EDA; ectodysplasin A; ED1; HED; EDA1; EDA2; XHED; XLHED; ED1-A1; ED1-A2; STHAGX1; ectodysplasin-A; ectodermal dysplasia protein; X-linked anhidroitic ectodermal dysplasia protein |
Gene ID : | 1896 |
mRNA Refseq : | NM_001005609 |
Protein Refseq : | NP_001005609 |
MIM : | 300451 |
UniProt ID : | Q92838 |
Chromosome Location : | Xq12-q13.1 |
Pathway : | Cytokine-cytokine receptor interaction |
Function : | protein binding; receptor binding; tumor necrosis factor receptor binding |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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