Recombinant Mouse Tnfrsf18, Fc Chimera
Cat.No. : | Tnfrsf18-2087M |
Product Overview : | Recombinant MouseTnfrsf18 Produced inHEK 293 cells.The cysteine-rich region of mouse GITR (aa 20-152) is fused to the Fc portion of human IgG1. MW=45kDa (SDS-PAGE). |
- Specification
- Gene Information
- Related Products
Cat. No. : | Tnfrsf18-2087M |
Description : | GITR (glucocorticoid-induced tumor necrosis factor receptor) also known as TNFRSF18, is a surface receptor molecule that has been shown to be involved in inhibiting the suppressive activity of T-regulatory cells and extending the survival of T-effector cells.1 GITR is involved in the regulation of T-cell receptor mediated cell death. Constitutive expression of a transfected GITR gene induces resistance to apoptosis induced by anti CD3 monoclonal antibodies. |
Source : | HEK 293 cells. |
Concentration : | 1mg/ml after reconstitution. |
Purity : | ≥90% (SDS-PAGE). |
Formulation : | Lyophilized. Contains PBS. |
Endotoxin Content : | <0.1EU/µg purified protein (LAL test; Bio Whittaker). |
Reconstitution : | Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein. |
Specificity : | Binds mouse GITRL. |
Term Storage : | -20°C. |
Handling : | Stable for at least 6 months after receipt when stored at -20°C. |
Stability : | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C. |
Gene Name : | Tnfrsf18 tumor necrosis factor receptor superfamily, member 18 [ Mus musculus ] |
Synonyms : | Tnfrsf18; tumor necrosis factor receptor superfamily, member 18; AITR; Gitr;tumor necrosis factor receptor superfamily member 18; OTTMUSP00000011817; OTTMUSP00000011818; glucocorticoid-induced TNFR-related protein |
Gene ID : | 21936 |
mRNA Refseq : | NM_009400 |
Protein Refseq : | NP_033426 |
UniProt ID : | O35714 |
Chromosome Location : | 4 E |
Pathway : | Cytokine-cytokine receptor interaction |
Function : | protein binding; receptor binding |
Products Types
◆ Recombinant Protein | ||
TNFRSF18-1995H | Recombinant Human TNFRSF18 Protein, MYC/DDK-tagged | +Inquiry |
TNFRSF18-2769H | Recombinant Human TNFRSF18 Protein, His-tagged | +Inquiry |
TNFRSF18-148H | Recombinant Human TNFRSF18 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFRSF18-894M | Recombinant Mouse TNFRSF18 Protein (Met1-His153), MlgG1 Fc-tagged | +Inquiry |
TNFRSF18-662M | Recombinant Mouse TNFRSF18 Protein | +Inquiry |
◆ Lysates | ||
TNFRSF18-1245RCL | Recombinant Rat TNFRSF18 cell lysate | +Inquiry |
TNFRSF18-1143HCL | Recombinant Human TNFRSF18 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket