Recombinant Human Sp1 Transcription Factor

• Cat.No.: SP1-590H
• Product Overview: Recombinant human SP1 protein was expressed inSf9 insect cells.

Specification

• Cat. No.: SP1-590H
• Description: SP1 belongs to the family of zinc finger DNA binding proteins in mammalian cells. This protein mediates transcriptional activity through specific DNA sequences that are found in a number of viral and cellular gene promoters. SP1 has been shown to associate with other mammalian gene coactivator proteins to regulate gene transcription.
• Source: Sf9 insect cells.
• Formulation: 15 ug of recombinant SP1 protein in 5uM ZnSO4, 50 mM KCl, 2mM DTT, 12 mM HEPES-KOH (pH 7.5), 6 mM MgCl2, 0.1% NP40 and 50% glycerol.
• Applications: Useful for the stimulation of LSD1 enzyme activity.
• Storage: Store at -70º C. Avoid multiple freeze/thaw cycles.
• Pathways: Huntington"s disease; TGF-beta signaling pathway

Gene Information

• Gene Name: SP1 Sp1 transcription factor [ Homo sapiens ]
• Synonyms: SP1; Sp1 transcription factor; Sp1 transcription factor; specificity protein 1; TSFP1; Transcription factor Sp1
• Gene ID: 6667
• mRNA Refseq: NM_003109
• Protein Refseq: NP_003100
• MIM: 189906
• UniProt ID: P08047
• Chromosome Location: 12q13.1
• Function: DNA binding; RNA polymerase II transcription factor activity; double-stranded DNA binding; histone deacetylase binding; metal ion binding; promoter binding; protein C-terminus binding; protein homodimerization activity; transcription activator activity; transcription factor activity; zinc ion binding