| Cat. No. | CABT-54666RM |
| Antigen Description | Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) also known as CD39 (Cluster of Differentiation 39), is a human gene. |
| Product Overview | RAT ANTI MOUSE CD39 Monoclonal Antibody,RPE |
| Immunogen | A CD39 expression construct and a final boost with CD39-transfected HEK cells. |
| Isotype | IgG2a |
| Specificity | CABT-54666RM recognises CD39, also known as Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) or Ecto-ATP diphosphohydrolase. CD39 was first described as a B cell activation marker, but is also expressed on natural killer cells, monocytes, dendritic cells and subsets of activated T cells. It is critical in the regulation of leukocyte accumulation within hypoxic tissues and plays a role in the thromboregulation of platelet and endothelial function activation. CD39, along with CD73, distinguishes regulatory T cells from other resting or activated T cells and plays a role in the suppressive action of regulatory T cells. |
| Application | Flow Cytometry |
| Form | Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised |
| Storage Buffer | Store at +4oC or at -20oC if preferred.Storage in frost-free freezers is not recommended.This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Buffer Stabilisers | Buffer Solution:Phosphate buffered saline
Preservative Stabilisers:0.09% Sodium Azide (NaN3) 1% Bovine Serum Albumin 5% Sucrose |
| Reactivity | Mouse |
| Preparation | Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant |
| Shelf Life | 18 months from date of despatch. |
| Clone | Evib60 |
| Host | Rat |
| Antigen Gene Information | Gene Name | Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 [ Mus musculus ] |
| Official symbol | Entpd1 |
| Synonyms | Entpd1; Cd39; AA408691; NTPDase-1; 2610206B08Rik; ectonucleoside triphosphate diphosphohydrolase 1 |
| GeneId | 12495 |
| Pathway | Purine metabolism, organism-specific biosystem |
| Function | ATP binding; hydrolase activity; nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; nucleotide binding |
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