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Recombinant Human NOS2, His-Flag-tagged

Cat.No. : NOS2-611H
Product Overview : Recombinant Human NOS2(a.a. 2 – 1153) fussed with His-Flag tag at N-terminal was expressed in a baculovirus infected Sf9 cell expression system.
  • Specification
  • Gene Information
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Description : Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17.
Source : Insect cell
Species : Human
Tag : His-Flag
Form : 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 80 ng/µl FLAG peptide, and 20% glycerol.
Molecular Mass : MW= 133 kDa
AA Sequence : MHHHHHHDYKDDDDKACPWKFLFKT KFHQYAMNGEKDINNNVEKAPCATS SPVTQDDLQYHNLSKQQNESPQPL VETGKKSPESLVKLDATPLSSPRHV RIKNWGSGMTFQDTLHHKAKGILTC RSKSCLGSIMTPKSLTRGPRDKPT PPDELLPQAIEFVNQYYGSFKEAKI EEHLARVEAVTKEIETTGTYQLTGD ELIFATKQAWRNAPRCIGRIQWSN LQVFDARSCSTAREMFEHICRHVRY STNNGNIRSAITVFPQRSDGKHDFR VWNAQLIRYAGYQMPDGSIRGDP ANVEFTQLCIDLGWKPKYGRFDVVP LVLQANGRDPELFEIPPDLVLEVAM EHPKYEWFRELELKWYALPAVANM LLEVGGLEFPGCPFNGWYMGTEIGV RDFCDVQRYNILEEVGRRMGLETHK LASLWKDQAVVEINIAVLHSFQKQ NVTIMDHHSAAESFMKYMQNEYRSR GGCPADWIWLVPPMSGSITPVFHQE MLNYVLSPFYYYQVEAWKTHVWQ DEKRRPKRREIPLKVLVKAVLFACM LMRKTMASRVRVTILFATETGKSEA LAWDLGALFSCAFNPKVVCMDKYR LSCLEEERLLLVVTSTFGNGDCPGN GEKLKKSLFMLKELNNKFRYAVFGL GSSMYPRFCAFAHDIDQKLSHLGA SQLTPMGEGDELSGQEDAFRSWAVQ TFKAACETFDVRGKQHIQIPKLYTS NVTWDPHHYRLVQDSQPLDLSKAL SSMHAKNVFTMRLKSRQNLQSPTSS RATILVELSCEDGQGLNYLPGEHLG VCPGNQPALVQGILERVVDGPTP HQTVRLEALDESGSYWVSDKRLPPC SLSQALTYFLDITTPPTQLLLQKLA QVATEEPERQRLEALCQPSEYSKW KFTNSPTFLEVLEEFPSLRVSAGFL LSQLPILKPRFYSISSSRDHTPTEI HLTVAVVTYHTRDGQGPLHHGVCS TWLNSLKPQDPVPCFVRNASGFHLP EDPSHPCILIGPGTGIAPFRSFWQQ RLHDSQHKGVRGGRMTLVFGCRR PDEDHIYQEEMLEMAQKGVLHAVHT AYSRLPGKPKVYVQDILRQQLASEV LRVLHKEPGHLYVCGDVRMARDVA HTLKQLVAAKLKLNEEQVEDYFFQL KSQKRYHEDIFGAVFPYEAKKDRVA VQPSSLEMSAL
Purity : ≥95%
Applications : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Stability : >6 months at –80 centigrade
Concentration : 0.15 mg/ml
Warning : Avoid freeze/thaw cycles.
Gene Name : NOS2 nitric oxide synthase 2, inducible [ Homo sapiens ]
Official Symbol : NOS2
Synonyms : NOS; INOS; NOS2A; HEP-NOS; nitric oxide synthase, inducible; NOS type II; NOS, type II; hepatocyte NOS; inducible NO synthase; inducible NOS; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, macrophage; peptidyl-cysteine S-nitrosylase NOS2
Gene ID : 4843
mRNA Refseq : NM_000625
Protein Refseq : NP_000616
MIM : 163730
UniProt ID : P35228
Chromosome Location : 17q11.2
Pathway : AGE/RAGE pathway, organism-specific biosystem; ATF-2 transcription factor network, organism-specific biosystem; Calcium signaling pathway, conserved biosystem
Function : FMN binding; NADPH-hemoprotein reductase activity; iron ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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