Recombinant Human Histone Cluster 1, H1d

• Cat.No.: HIST1H1D-2133H

Specification

• Cat. No.: HIST1H1D-2133H
• Description: Histone H1.3 is a protein that in humans is encoded by the HIST1H1D gene. Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
• Source/Host: E. coli.
• Purity: ≥95% (HPLC).
• MW: ~22kDa.
• Formulation: Lyophilized.
• Solubility: Soluble in 100% ethanol, methanol, DMSO or aqueous solutions.
• Long Term Storage: -20°C.
• Handling: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: HIST1H1D histone cluster 1, H1d [ Homo sapiens ]
• Synonyms: histone cluster 1, H1d; H1.3; H1F3; MGC138176; HIST1H1D; histone H1.3; histone H1c; histone 1, H1d; H1 histone family, member 3;Histone H1c
• Gene ID: 3007
• mRNA Refseq: NM_005320
• Protein Refseq: NP_005311
• MIM: 142210
• UniProt ID: H1 histone family, member 3
• Chromosome Location: 6p21.3
• Pathway: Apoptosis
• Function: protein binding; DNA binding