Recombinant Human CADM3 protein, His-tagged
Cat.No. : | CADM3-2184H |
Product Overview : | Recombinant Human CADM3 (Asn25-His330) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
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Description : | Cell adhesion molecule 3 (CADM3) is also known as Synaptic cell adhesion molecule 3 (SynCAM3), Immunoglobulin superfamily member 4B (IgSF4B), Brain immunoglobulin receptor (BIgR), Nectin-like protein 1 (NECL-1), TSLC1-like protein 1 (TSLL1), which belongs to the nectin family. CADM3 contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain.The isoform 1 is expressed mainly in adult and fetal brain and isoform 2 is highly expressed in adult brain and weakly expressed in placenta. In brain, Isoform 2 is highly expressed in cerebellum. CADM3 involved in the cell-cell adhesion and has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3. CADM3 / SynCAM3 interaction with EPB41L1 may regulate structure or function of cell-cell junctions. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Asn25 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 34.5 kDa. The protein migrates as 38-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Asn25-His330 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | CADM3 |
Official Symbol : | CADM3 |
Synonyms : | CADM3; cell adhesion molecule 3; IGSF4B, immunoglobulin superfamily, member 4B; BIgR; FLJ10698; Necl 1; NECL1; nectin like 1; SynCAM3; TSLL1; TSLC1-like 1; nectin-like 1; TSLC1-like protein 1; nectin-like protein 1; brain immunoglobulin receptor; synaptic cell adhesion molecule 3; immunoglobulin superfamily member 4B; immunoglobulin superfamily, member 4B; dendritic cell nectin-like protein 1 short isoform; IGSF4B; Necl-1; synCAM3 |
Gene ID : | 57863 |
mRNA Refseq : | NM_001127173 |
Protein Refseq : | NP_001120645 |
MIM : | 609743 |
UniProt ID : | Q8N126 |
Products Types
◆ Recombinant Protein | ||
Cadm3-1932M | Recombinant Mouse Cadm3 Protein, Myc/DDK-tagged | +Inquiry |
CADM3-186H | Recombinant Human CADM3 Protein, His-tagged | +Inquiry |
Cadm3-3301M | Recombinant Mouse Cadm3 protein(Met1-His328), His-tagged | +Inquiry |
CADM3-745R | Recombinant Rat CADM3 Protein, His (Fc)-Avi-tagged | +Inquiry |
CADM3-113H | Recombinant Human CADM3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CADM3-2556HCL | Recombinant Human CADM3 cell lysate | +Inquiry |
CADM3-738RCL | Recombinant Rat CADM3 cell lysate | +Inquiry |
CADM3-2275MCL | Recombinant Mouse CADM3 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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