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Active Recombinant Human B4GALT1 protein, His-tagged

Cat.No. : B4GALT1-646H
Product Overview : Recombinant Human B4GALT1 protein (NP_001488.2) (Gly 44-Ser 398) was fused with a polyhistidine tag at the N-terminus.
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Source : HEK293
Species : Human
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4
Bio-activity : B4GALT1 treated IgG1 Fc showed a significantly higher proportion of galactosylated component (G2 component) compared with the untreated sample (78.27% vs 9.34%).
Molecular Mass : The secreted recombinant human B4GALT1 consists of 371 amino acids and predicts a molecular mass of 41.5 kDa. By SDS-PAGE under reducing conditions, rh B4GALT1 migrates as an approximately 45-55 kDa protein due to glycosylation.
Protein Length : Gly 44-Ser 398
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : ≥ 92 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Reconstitution : Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.
Gene Name : B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 [ Homo sapiens ]
Official Symbol : B4GALT1
Synonyms : B4GALT1; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1; GGTB2; beta-1,4-galactosyltransferase 1; beta4Gal T1; lactose synthase; beta-1,4-GalTase 1; glycoprotein-4-beta-galactosyltransferase 2; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1; GT1; GTB; CDG2D; B4GAL-T1; beta4Gal-T1; MGC50983; DKFZp686N19253
Gene ID : 2683
mRNA Refseq : NM_001497
Protein Refseq : NP_001488
MIM : 137060
UniProt ID : P15291

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does B4GALT1 contribute to the synthesis of glycoproteins and glycolipids? 09/05/2022

It synthesizes lactosylceramide, a building block for complex glycosphingolipids in glycoprotein and glycolipid synthesis.

What is the primary function of B4GALT1 in cellular processes? 03/14/2022

B4GALT1 is crucial for glycosylation, attaching galactose to proteins and lipids.

In which cells or tissues is B4GALT1 predominantly expressed? 01/03/2022

B4GALT1 is widely expressed but has higher activity in the liver, kidney, and intestine.

What therapeutic strategies are being explored targeting B4GALT1 for disease treatment? 02/09/2020

Therapeutic strategies include targeting B4GALT1 to modulate its activity in cancer and other diseases.

How is B4GALT1 implicated in cancer progression and metastasis? 11/14/2019

Altered B4GALT1 expression is linked to cancer, influencing tumor growth and metastasis.

Are there known genetic mutations in B4GALT1 associated with specific diseases or conditions? 08/27/2019

Genetic mutations in B4GALT1 are associated with some rare metabolic disorders.

What role does B4GALT1 play in immune system function? 02/27/2019

It modulates immune responses by altering glycosylation patterns on immune cells.

Customer Reviews (3)

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10/14/2021

    Quick shipping, excellent quality.

    10/03/2021

      High quality, excellent performance.

      05/16/2021

        Reliable, good for research.

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