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Cat.No.
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CPBT-26021RH
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Product Overview
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Rabbit Polyclonal antibody to Human APEH.
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Antigen Description
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This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
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Isotype
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IgG
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Immunogen
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KLH conjugated synthetic peptide selected from the N-terminal region of Human AARE.
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Host
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Rabbit
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Species
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Human
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Formulation
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Liquid
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Purity Detail
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Ammonium Sulphate Precipitation
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Applications
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WB, ELISA
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Storage buffer
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Preservative: 0.09% Sodium Azide Constituents: PBS
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Storage
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Shipped at 4oC. Upon delivery aliquot and store at -20oC. Avoid freeze / thaw cycles.
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Antigen Gene Information
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Gene Name
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APEH N-acylaminoacyl-peptide hydrolase [ Homo sapiens ]
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Official Symbol
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APEH
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Synonyms
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APEH; N-acylaminoacyl-peptide hydrolase; D3F15S2, D3S48E, DNF15S2; acylamino-acid-releasing enzyme; AARE; ACPH; Acyl peptide hydrolase; Acylamino acid releasing enzyme; Acylaminoacyl peptidase; APEH; APH; N acylaminoacyl peptide hydrolase; OPH; Oxidized protein hydrolase; AARE; acyl-peptide hydrolase; acylaminoacyl-peptidase; oxidized protein hydrolase; APH; OPH; ACPH; D3S48E; D3F15S2; DNF15S2;
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GeneID
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327
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mRNA Refseq
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NM_001640
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Protein Refseq
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NP_001631
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MIM
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102645
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Uniprot ID
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P13798
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Chromosome Location
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3p21
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Function
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hydrolase activity; serine-type endopeptidase activity;
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Download Datasheet:
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