Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human SGTA, His-tagged

Cat.No. : SGTA-2359H
Product Overview : Recombinant human SGTA protein, fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. 35.1 kDa (321aa).
  • Specification
  • Gene Information
  • Related Products
Cat. No. : SGTA-2359H
Description : SGTA, also known as SGT or hSGT, is a ubiquitously expressed protein that contains three TPR protein-protein interaction repeats. This protien is believed to function as a component of the androgen receptor (AR)-chaperone-cochaperone complex, acting as a cochaperone involved in androgen signaling. In addition, SGTA functions as a cochaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. On the basis of its role in apoptosis and androgen signaling, SGTA is a potential candidate for PCOS (polycystic ovary syndrome), a disorder characterized by androgen excess, obesity and menstrual disturbances.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT.
Purity : > 95% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MDNKKRLAYA IIQFLHDQLR HGGLSSDAQE SLEVAIQCLE TAFGVTVEDS DLALPQTLPE IFEAAATGKE MPQDLRSPAR TPPSEEDSAE AERLKTEGNE QMKVENFEAA VHFYGKAIEL NPANAVYFCN RAAAYSKLGN YAGAVQDCER AICIDPAYSK AYGRMGLALS SLNKHVEAVA YYKKALELDP DNETYKSNLK IAELKLREAP SPTGGVGSFD IAGLLNNPGF MSMASNLMNN PQIQQLMSGM ISGGNNPLGT PGTSPSQNDL ASLIQAGQQF AQQMQQQNPE LIEQLRSQIR SRTPSASNDD QQELEHHHHH H.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha [ Homo sapiens ]
Synonyms : SGTA; small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha; SGT; hSGT; alphaSGT; small glutamine-rich tetratricopeptide; protein containing three tetratricopeptide repeats
Gene ID : 6449
mRNA Refseq : NM_003021
Protein Refseq : NP_003012
MIM : 603419
UniProt ID : O43765
Chromosome Location : 19p13
Function : protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
Can the nutritional status of SGTA protein be improved by diet? 11/04/2022

There is no conclusive evidence that diet can improve the nutritional status of SGTA protein, but maintaining a balanced diet and moderate protein intake can help maintain good health.

What is the relationship between SGTA protein and cardiovascular disease? 02/03/2022

Studies have shown that SGTA protein may be associated with the onset of cardiovascular diseases such as atherosclerosis and myocardial infarction.

What is the current progress in drug development for SGTA? 07/06/2021

The drug development for SGTA is currently in the clinical trial stage, including small molecule inhibitors against SGTA and inhibitors against the SGTA signaling pathway.

Weather SGTA protein related to viral infection? 01/28/2021

Studies have shown that SGTA protein can be involved in the regulation of antiviral immune responses and affect the course of viral infection.

How is SGTA used as a biomarker in clinical practice? 07/13/2020

In clinical practice, the expression level of SGTA can be measured to predict the progression and prognosis of the disease, and to guide the choice of treatment regimen. For example, in the diagnosis and treatment of tumor diseases, detecting the expression level of SGTA can help doctors determine the type, stage and prognosis of the disease, and guide the choice of treatment regimen.

How can I increase the expression level of SGTA protein? 06/27/2020

At present, there is no direct way to increase the expression level of SGTA protein, but it can be improved by regulating gene expression and providing nutritional support.

Customer Reviews (3)

Write a review
Reviews
06/01/2022

    Around the colleagues are full of praise, the experiment effect is too good.

    11/20/2021

      Very easy to use and highly recommended.

      10/06/2021

        Good activity, can maintain long-term activity.

        Ask a Question for All SGTA Products

        Required fields are marked with *

        My Review for All SGTA Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends