Recombinant Human PTP4A3, GST-tagged

• Cat.No.: PTP4A3-676H
• Product Overview: Recombinant human PRL-3 was produced inE. coli.The catalytic domain of PRL-3 (aa 2-173) is fused at the N-terminus to a GST-tag. 45.4 kDa.

Specification

• Cat. No.: PTP4A3-676H
• Description: PRL phosphatases comprise a class of small phosphatases with oncogenic activity, which are prenylated at their C-termini. PRL-3 is overexpressed in colon tumors metastasizing to the liver, but not in normal colorectal epithelium.
• Source/Host: E. coli.
• Application: Study of enzyme kinetics and regulation, dephosphorylation of target substrates, and inhibitor screening.
• Long Term Storage: -20°C.

Gene Information

• Gene Name: PTP4A3 protein tyrosine phosphatase type IVA, member 3 [ Homo sapiens ]
• Synonyms: PTP4A3; protein tyrosine phosphatase type IVA, member 3; PRL3; PRL-3; PRL-R; potentially prenylated protein tyrosine phosphatase; EC 3.1.3.48
• Gene ID: 11156
• mRNA Refseq: NM_007079
• Protein Refseq: NP_009010
• MIM: 606449
• UniProt ID: O75365
• Chromosome Location: 8q24.3
• Function: hydrolase activity; identical protein binding; prenylated protein tyrosine phosphatase activity