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Recombinant Human Promyelocytic Leukemia, GST-tagged

Cat.No. : PML-2375H
Product Overview : Recombinant human PML SUMOylation site peptide produced inE.colias a GST-tagged protein, 28.459 kDa.
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  • Gene Information
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Cat. No. : PML-2375H
Description : A peptide representing the sequence of the primary PML SUMOylation site (Lys-490) and its surrounding amino acid residues (485-495) acts as a target protein for in vitro SUMOylation and has utility as a substrate for SUMO chain formation. Suggested uses :Substrate for in vitro SUMOylation reactions, Investigation of SUMO conjugation pathway and SUMO chain formation, GST pull down of SUMO modified PML species.
Source/Host : E.coli.
Purity : ≥95% (SDS-PAGE).
Long Term Storage : -80°C.
Gene Name : PML promyelocytic leukemia [ Homo sapiens ]
Synonyms : promyelocytic leukemia; MYL; RNF71; PP8675; TRIM19; PML; probable transcription factor PML; RING finger protein 71; promyelocytic leukemia protein; tripartite motif protein TRIM19; promyelocytic leukemia, inducer of; tripartite motif-containing protein 19; Tripartite motif-containing protein 19; RING finger protein 71
Gene ID : 5371
mRNA Refseq : NM_002675
Protein Refseq : NP_002666
MIM : 102578
UniProt ID : P29590
Chromosome Location : 15q22
Pathway : Acute myeloid leukemia; Endocytosis; Pathways in cancer; Ubiquitin mediated proteolysis
Function : protein homodimerization activity; transcription regulator activity; ubiquitin protein ligase binding; DNA binding; SMAD binding; metal ion binding; protein binding; zinc ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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